MORG1 抗体 (N-Term)
Quick Overview for MORG1 抗体 (N-Term) (ABIN3044326)
抗原
See all MORG1 (wdr83) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-43, N-Term
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原理
- Anti-Morg1/WDR83 Antibody
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序列
- RAVRFNVDGN YCLTC
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Morg1/WDR83 Antibody (ABIN3044326). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Morg1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-WD Repeat Domain 83 (wdr83) (AA 171-262) antibody
wdr83 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-WD Repeat Domain 83 (wdr83) (AA 201-315) antibodywdr83 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (AA 64-315) antibodywdr83 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) antibodywdr83 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (AA 171-262) antibodywdr83 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (AA 1-315) antibodywdr83 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (N-Term) antibodywdr83 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (Internal Region) antibodywdr83 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (Internal Region) antibodywdr83 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 83 (wdr83) (C-Term) antibodywdr83 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
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别名
- WDR83
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背景
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Synonyms: WD repeat domain-containing protein 83,Mitogen-activated protein kinase organizer 1,MAPK organizer 1,WDR83,MORG1,
Tissue Specificity: MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. .
Background: MORG1 (mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase (ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate, or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.
Sequence Similarities: Belongs to the WD repeat MORG1 family.
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分子量
- 12 kDa
抗原
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