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Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体

The 兔 多克隆 anti-Deoxyuridine Triphosphatase antibody (ABIN3044322) specifically detects Deoxyuridine Triphosphatase in WB, IHC, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN3044322
发货至: 中国
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Quick Overview for Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体 (ABIN3044322)

抗原

See all Deoxyuridine Triphosphatase (DUT) 抗体
Deoxyuridine Triphosphatase (DUT)

适用

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宿主

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克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    原理

    Anti-DUT Antibody

    序列

    KKGDRIAQLI CERIFYPE

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by two amino acids.

    产品特性

    Anti-DUT Antibody-1. Tested in ICC/IF, IHC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human DUT, different from the related rat and mouse sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Deoxyuridine Triphosphatase (DUT)

    别名

    DUT

    背景

    Background: Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low intracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. dUTPase activity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and dUTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the cytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35 % identity with the E.coli dUTPase and 53 % identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial forms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the use of alternative 5-prime exons. Human dUTPase exhibits 92 % identity with rat. Moreover, this enzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.

    Gene Full Name: deoxyuridine triphosphatase

    Sequence Similarities: Belongs to the dUTPase family.

    分子量

    18 kDa

    基因ID

    1854

    UniProt

    P33316
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