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Deoxyuridine Triphosphatase (DUT) (AA 212-229), (C-Term) 抗体

DUT 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044322
发货至: 中国
  • 抗原 See all Deoxyuridine Triphosphatase (DUT) 抗体
    Deoxyuridine Triphosphatase (DUT)
    抗原表位
    • 15
    • 15
    • 11
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
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    • 1
    AA 212-229, C-Term
    适用
    • 75
    • 31
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 72
    • 2
    • 1
    克隆类型
    • 74
    • 1
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 2
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    • 2
    • 2
    • 2
    非结合性
    应用范围
    • 64
    • 26
    • 26
    • 25
    • 22
    • 15
    • 8
    • 6
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(DUT) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    KKGDRIAQLI CERIFYPE
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(DUT) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: deoxyuridine triphosphatase
    Protein Name: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human DUT(212-229aa KKGDRIAQLICERIFYPE), different from the related rat and mouse sequences by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DUT Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    Deoxyuridine Triphosphatase (DUT)
    别名
    DUT (DUT 产品)
    别名
    BcDNA:LD08534 antibody, CG4584 antibody, Dmel\\CG4584 antibody, LD08534 antibody, UTPase antibody, anon-SAGE:Wang-077 antibody, dUTPase antibody, Tb07.27E10.390 antibody, dutpase antibody, 5031412I06Rik antibody, 5133400F09Rik antibody, D2Bwg0749e antibody, Dutp antibody, PIP4 antibody, deoxyuridine triphosphatase antibody, Deoxyuridine triphosphatase antibody, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 antibody, involved in nucleotide metabolism antibody, tegument protein antibody, dUTPase antibody, deoxyuridine triphosphatase L homeolog antibody, DUT antibody, dUTPase antibody, P18 antibody, AlHV1gp51 antibody, UL50 antibody, HVT058 antibody, ORF9 antibody, ORF8 antibody, U45 antibody, GAMMAHV.ORF54 antibody, Tc00.1047053509151.130 antibody, Tc00.1047053508175.160 antibody, Tb927.7.5160 antibody, dut.L antibody, Dut antibody
    物质类
    Viral Protein
    背景
    Deoxyuridine triphosphate nucleotidohydrolase(dUTPase) is responsible for maintaining low intracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. dUTPase activity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and dUTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the cytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35 % identity with the E.coli dUTPase and 53 % identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial forms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the use of alternative 5-prime exons. Human dUTPase exhibits 92 % identity with rat. Moreover, this enzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.

    Synonyms: Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isoform antibody|Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial antibody|Deoxyuridine triphosphatase antibody|dut antibody|DUT_HUMAN antibody|dUTP nucleotidohydrolase antibody|dUTP pyrophosphatase antibody|dUTPase antibody|FLJ20622 antibody
    UniProt
    P33316
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