Myoglobin 抗体 (C-Term)
Quick Overview for Myoglobin 抗体 (C-Term) (ABIN3044306)
抗原
See all Myoglobin (MB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 138-154, C-Term
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原理
- Anti-Myoglobin/MB Antibody Picoband®
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序列
- LFRNDIAAKY KELGFQG
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
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Rabbit IgG polyclonal antibody for Myoglobin(MB) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: myoglobin
Protein Name: myoglobin -
纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Myoglobin, identical to the related rat sequence.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
1. Boyer, S. H., Fainer, D. C., Naughton, M. A. Myoglobin inherited structural variation in man. Science 140: 1228-1231, 1963. 2. Boulton, F. E., Huntsman, R. G., Lorkin, P. A., Lehmann, H. Abnormal human myoglobin: 53(D4) glutamic acid lysine. Nature 223: 832-833, 1969. 3. Jeffreys, A. J., Wilson, V., Blanchetot, A., Weller, P., Geurts van Kessel, A., Spurr, N., Solomon, E., Goodfellow, P. The human myoglobin gene: a third dispersed globin locus in the human genome. Nucleic Acids Res. 12: 3235-3243, 1984. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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Synthesis and in vitro evaluation of a hyaluronic acid-quantum dots-melphalan conjugate." in: Carbohydrate polymers, Vol. 121, pp. 132-9, (2015) (PubMed).
: "A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells." in: Biochemical and biophysical research communications, Vol. 409, Issue 2, pp. 344-9, (2011) (PubMed).
: "
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Synthesis and in vitro evaluation of a hyaluronic acid-quantum dots-melphalan conjugate." in: Carbohydrate polymers, Vol. 121, pp. 132-9, (2015) (PubMed).
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- Myoglobin (MB)
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别名
- Myoglobin
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背景
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Synonyms: Myoglobin,Mb,
Background: Myoglobin (MB) also known as PVALB, is a single-chain globular protein of 153 or 154 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. It is a member of the globin superfamily and is expressed in skeletal and cardiac muscles. This gene is mapped to chromosome 22q11-q13. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure.
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分子量
- 17 kDa
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UniProt
- P04247
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途径
- Brown Fat Cell Differentiation
抗原
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