PAK6 抗体 (N-Term)
Quick Overview for PAK6 抗体 (N-Term) (ABIN3044285)
抗原
See all PAK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-32, N-Term
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原理
- Anti-PAK6 Antibody Picoband®
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序列
- QNFQHRVHTS FDPKEGK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-PAK6 Antibody (ABIN3044285). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PAK6, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-P21-Activated Kinase 6 (PAK6) (AA 268-297) antibody
PAK6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 1-681) antibodyPAK6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 268-297) antibodyPAK6 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB31991 unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 1-270) antibodyPAK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (Linker Domain) antibodyPAK6 适用: 人, 马, 犬, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (N-Term) antibodyPAK6 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 猴, Bat, 小鸡 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 1-270) antibodyPAK6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (N-Term) antibodyPAK6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 275-305), (Middle Region) antibodyPAK6 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 116-146) antibodyPAK6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Gross, M. B. Personal Communication. Baltimore, Md. 5/10/2011. 2. Yang, F., Li, X., Sharma, M., Zarnegar, M., Lim, B., Sun, Z. Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. J. Biol. Chem. 276: 15345-15353, 2001. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PAK6 (P21-Activated Kinase 6 (PAK6))
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别名
- PAK6
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背景
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Synonyms: Serine/threonine-protein kinase PAK 6,2.7.11.1,PAK-5,p21-activated kinase 6,PAK-6,PAK6,PAK5,
Tissue Specificity: Selectively expressed in brain and testis, with lower levels in multiple tissues including prostate and breast. .
Background: Serine/threonine-protein kinase PAK 6 (p21 Protein-activated Kinase 6) is an enzyme that in humans is encoded by the PAK6 gene. The PAK6 gene is mapped to chromosome 15q15. based on an alignment of the PAK6 sequence with the genomic sequence. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
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分子量
- 75 kDa
抗原
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