HSD17B4 抗体 (C-Term)
Quick Overview for HSD17B4 抗体 (C-Term) (ABIN3044284)
抗原
See all HSD17B4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 744-761, C-Term
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原理
- Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody Picoband®
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序列
- NIMLSQKLQM ILKDYAKL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody (ABIN3044284). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of Hydroxysteroid(17-beta) Dehydrogenase 4, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) antibody
HSD17B4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (N-Term) antibodyHSD17B4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (C-Term) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 437-736) antibodyHSD17B4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 510-736) antibodyHSD17B4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (N-Term) antibodyHSD17B4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 341-370) antibodyHSD17B4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31274 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4) (AA 340-370), (Middle Region) antibodyHSD17B4 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: HSD17B4 Hydroxysteroid (17-beta) dehydrogenase 1". 2. Aka JA, Mazumdar M, Chen CQ, Poirier D, Lin SX (Apr 2010). "17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production".Molecular Endocrinology. 24 (4): 832-45. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
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别名
- HSD17B4
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背景
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Synonyms: Peroxisomal multifunctional enzyme type 2,MFE-2,17-beta-hydroxysteroid dehydrogenase 4,17-beta-HSD 4,D-bifunctional protein,DBP,Multifunctional protein 2,MPF-2,Short chain dehydrogenase/reductase family 8C member 1, (3R)-hydroxyacyl-CoA dehydrogenase,1.1.1.n12,Enoyl-CoA hydratase 2,4.2.1.107,4.2.1.119,3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase,HSD17B4,EDH17B4, SDR8C1,
Tissue Specificity: Present in many tissues with highest concentrations in liver, heart, prostate and testis.
Background: Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Sequence Similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
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分子量
- 80 kDa
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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