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- 抗原 See all TACR1 抗体
- TACR1 (Tachykinin Receptor 1 (TACR1))
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抗原表位
- AA 231-245, Middle Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TACR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Substance-P receptor(TACR1) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- DSSDRYHEQV SAKRK
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Substance-P receptor(TACR1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: tachykinin receptor 1
Protein Name: Substance-P receptor(SPR) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TACR1(231-245aa DSSDRYHEQVSAKRK), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product TACR1 Primary Antibody
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anti-Tachykinin Receptor 1 (TACR1) (AA 2-50) antibody
TACR1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) (C-Term) antibodyTACR1 适用: 人, 大鼠, 豚鼠, 猴, 兔, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) (Internal Region) antibodyVerified TACR1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) (2nd Extracellular Loop), (AA 180-194) antibodyTACR1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) (2nd Extracellular Loop), (AA 180-194) antibody (Atto 488)TACR1 适用: 人, 大鼠, 小鼠 IHC, IF, FACS 宿主: 兔 Polyclonal Atto 488
anti-Tachykinin Receptor 1 (TACR1) (AA 1-29) antibodyTACR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) (AA 140-243) antibodyTACR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) (Extracellular Domain) antibodyTACR1 适用: 人, 犬, 猴, Cow IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tachykinin Receptor 1 (TACR1) antibodyMicroarray verified TACR1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB323175 unconjugated
anti-Tachykinin Receptor 1 (TACR1) antibodyMicroarray verified TACR1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB139563 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- TACR1 (Tachykinin Receptor 1 (TACR1))
- 别名
- TACR1 (TACR1 产品)
- 别名
- NK1R antibody, NKIR antibody, SPR antibody, TAC1R antibody, Nk1r antibody, Spr antibody, Tac1r antibody, nk1R antibody, Tacr1 antibody, ASPR antibody, tachykinin receptor 1 antibody, TACR1 antibody, Tacr1 antibody
- 背景
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The tachykinin receptor 1(TACR1) also known as neurokinin 1 receptor(NK1R) or substance P receptor(SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins. The protein is the product of the TACR1 gene. Tachykinin receptor 1 consists of 407 amino acid residues, and it has a molecular weight of 58.000. Tachykinin receptor 1, as well as the other tachykinin receptors, is made of seven hydrophobic transmembrane(TM) domains with three extracellular and three intracellular loops, an amino-terminus and a cytoplasmic carboxy-terminus. The loops have functional sites, including two cysteines amino acids for a disulfide bridge, Asp-Arg-Tyr, which is responsible for association with arrestin and, Lys/Arg-Lys/Arg-X-X-Lys/Arg, which interacts with G-proteins.The tachykinin receptor 1 can be found in both the central and peripheral nervous system. It is present in neurons, brainstem, vascular endothelial cells, muscle, gastrointestinal tracts, genitourinary tract, pulmonary tissue, thyroid gland and different types of immune cells. The binding of SP to the tachykinin receptor 1 has been associated with the transmission of stress signals and pain, the contraction of smooth muscles and inflammation. Tachykinin receptor 1 antagonists have also been studied in migraine, emesis and psychiatric disorders. In fact, aprepitant has been proved effective in a number of pathophysiological models of anxiety and depression. Other diseases in which the tachykinin receptor 1 system is involved include asthma, rheumatoid arthritis and gastrointestinal disorders.
Synonyms: neurokinin 1 antibody|NK 1 receptor antibody|NK 1R antibody|NK-1 receptor antibody|NK-1R antibody|NK1 receptor antibody|NK1R antibody|NK1R_HUMAN antibody|NKIR antibody|SPR antibody|Substance P receptor antibody|Substance-P receptor antibody|TAC 1R antibody|TAC1R antibody|Tachykinin 1 receptor(substance P receptor neurokinin 1 receptor) antibody|Tachykinin receptor 1 antibody|Tachykinin receptor 1(substance P receptor neurokinin 1 receptor) antibody|TACR1 antibody - UniProt
- P25103
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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