ITGA3 抗体 (N-Term)
Quick Overview for ITGA3 抗体 (N-Term) (ABIN3044222)
抗原
See all ITGA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-67, N-Term
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原理
- Anti-Integrin alpha 3/ITGA3 Antibody Picoband®
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序列
- LFGYSVALHR QTERQQR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Integrin alpha 3/ITGA3 Antibody (ABIN3044222). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Integrin, alpha 3 (ITGA3) (AA 33-236) antibody
ITGA3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 63-248) antibodyITGA3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5F1D4 unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 63-248) antibodyITGA3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H2A11 unconjugated
anti-Integrin, alpha 3 (ITGA3) (N-Term) antibodyITGA3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 976-1025) antibodyITGA3 适用: 小鼠, Pig WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) antibodyITGA3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 168-276) antibodyITGA3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) antibodyITGA3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 165-199), (N-Term) antibodyITGA3 适用: 人 WB 宿主: 兔 Polyclonal RB52792 unconjugated
anti-Integrin, alpha 3 (ITGA3) (Internal Region) antibodyITGA3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
1. Akula, S. M., Pramod, N. P., Wang, F.-Z., Chandran, B. Integrin alpha-3/beta-1 (CD 49c/29) is a cellular receptor for Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) entry into the target cells. Cell 108: 407-419, 2002. 2. Dulabon, L., Olson, E. C., Taglienti, M. G., Eisenhuth, S., McGrath, B., Walsh, C. A., Kreidberg, J. A., Anton, E. S. Reelin binds alpha-3-beta-1 integrin and inhibits neuronal migration. Neuron 27: 33-44, 2000. 3. Takada Y, Murphy E, Pil P, Chen C, Ginsberg MH, Hemler ME (Oct 1991). "Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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别名
- ITGA3
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背景
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Synonyms: Integrin alpha-3,CD49 antigen-like family member C,FRP-2,Galactoprotein B3,GAPB3,VLA-3 subunit alpha,CD49c,Integrin alpha-3 heavy chain,Integrin alpha-3 light chain,ITGA3,MSK18,
Tissue Specificity: Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. .
Background: ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.
Sequence Similarities: Belongs to the integrin alpha chain family.
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分子量
- 155 kDa
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UniProt
- P26006
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途径
- CXCR4-mediated Signaling Events, Integrin Complex
抗原
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