HSF2 抗体 (Middle Region)
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北京 101111
Quick Overview for HSF2 抗体 (Middle Region) (ABIN3044217)
抗原
See all HSF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Heat shock factor protein 2 HSF2 Antibody
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序列
- KQERDGPVEF QHPYFKQGQD D
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse sequence,and different from the related rat sequence by one amino acid.
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产品特性
- Anti-Heat shock factor protein 2 HSF2 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human HSF2, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
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亚型
- IgG
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anti-Heat shock factor protein 2 (HSF2) (AA 401-536) antibody
HSF2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 1-230) antibodyHSF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F11-A3 unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 79-173) antibodyHSF2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (Internal Region) antibodyHSF2 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 294-518) antibodyHSF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 1-230) antibodyHSF2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 396-445) antibodyHSF2 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 48-97) antibodyHSF2 适用: 人, 大鼠, 兔, Cow, 豚鼠, 猴, Pig, 马, 斑马鱼, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 441-490) antibodyHSF2 适用: 人, 大鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat shock factor protein 2 (HSF2) (AA 1-200) antibodyHSF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.01 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HSF2 (Heat shock factor protein 2 (HSF2))
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别名
- HSF2
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背景
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Background: HSF2 (HEAT-SHOCK TRANSCRIPTION FACTOR 2), also called HEAT-SHOCK FACTOR 2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. The International Radiation Hybrid Mapping Consortium maps the HSF2 gene to chromosome 6. Mouse Hsf2 was expressed in all 3 embryonic layers at embryonic day 7.5 and that the head fold was strongly stained at embryonic day 8.5. In adults, Hsf2 expression is detected in spermatocytes and spermatogonia, but not in elongated spermatids, spermatozoa, or Sertoli cells. Hsp70i bookmarking is mediated by a transcription factor called HSF2, which binds this promoter in mitotic cells, recruits protein phosphatase-2A, and interacts with the CAPG subunit of the condensin enzyme to promote efficient dephosphorylation and inactivation of condensin complexes in the vicinity, thereby preventing compaction at this site. And Hsf2-null mice were born at the expected mendelian ratio but had brain abnormalities and meiotic and gametogenic defects in both genders.
Gene Full Name: heat shock transcription factor 2
Sequence Similarities: Belongs to the HSF family.
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分子量
- 60 kDa
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基因ID
- 3298
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UniProt
- Q03933
抗原
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