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HSPB2 抗体 (Middle Region)

HSPB2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044185
发货至: 中国
  • 抗原 See all HSPB2 抗体
    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
    抗原表位
    • 14
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 102-118, Middle Region
    适用
    • 30
    • 23
    • 22
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 4
    克隆类型
    • 46
    • 4
    多克隆
    标记
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSPB2 antibody is un-conjugated
    应用范围
    • 36
    • 18
    • 14
    • 12
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    Anti-Heat shock protein beta-2 HSPB2 Antibody Picoband®
    序列
    RHPQRLDRHG FVSREFC
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-Heat shock protein beta-2 HSPB2 Antibody (ABIN3044185). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human HSPB2, identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product HSPB2 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human, Mouse
    Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
    1. Iwaki, A., Nagano, T., Nakagawa, M., Iwaki, T., Fukumaki, Y. Identification and characterization of the gene encoding a new member of the alpha-crystallin/Small hsp family, closely linked to the alpha-B-crystallin gene in a head-to-head manner. Genomics 45: 386-394, 1997.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(F) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
    别名
    HSPB2 (HSPB2 产品)
    背景

    Synonyms: Heat shock protein beta-2,HspB2,DMPK-binding protein,MKBP,HSPB2,

    Tissue Specificity: Expressed preferentially in skeletal muscle and heart but not in the lens.

    Background: Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein (HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al. (1997) identified a gene transcribed in the opposite ion. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al. (1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.

    Sequence Similarities: Belongs to the small heat shock protein (HSP20) family.

    分子量
    23 kDa
    UniProt
    Q16082
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