HSPB2 抗体 (Middle Region)
Quick Overview for HSPB2 抗体 (Middle Region) (ABIN3044185)
抗原
See all HSPB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-118, Middle Region
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原理
- Anti-Heat shock protein beta-2 HSPB2 Antibody Picoband®
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序列
- RHPQRLDRHG FVSREFC
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Heat shock protein beta-2 HSPB2 Antibody (ABIN3044185). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human HSPB2, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 12-170) antibody
HSPB2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 1-182) antibodyHSPB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B9E2 unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 12-182) antibodyHSPB2 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 1-182) antibodyHSPB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (Internal Region) antibodyHSPB2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 1-182) antibodyHSPB2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 1-182) antibodyHSPB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (C-Term) antibodyHSPB2 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (AA 101-182) antibodyHSPB2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 27kDa Protein 2 (HSPB2) (C-Term) antibodyHSPB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human, Mouse
Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
1. Iwaki, A., Nagano, T., Nakagawa, M., Iwaki, T., Fukumaki, Y. Identification and characterization of the gene encoding a new member of the alpha-crystallin/Small hsp family, closely linked to the alpha-B-crystallin gene in a head-to-head manner. Genomics 45: 386-394, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
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别名
- HSPB2
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背景
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Synonyms: Heat shock protein beta-2,HspB2,DMPK-binding protein,MKBP,HSPB2,
Tissue Specificity: Expressed preferentially in skeletal muscle and heart but not in the lens.
Background: Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein (HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al. (1997) identified a gene transcribed in the opposite ion. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al. (1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.
Sequence Similarities: Belongs to the small heat shock protein (HSP20) family.
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分子量
- 23 kDa
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UniProt
- Q16082
抗原
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