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SNAP23 抗体 (C-Term)

This anti-SNAP23 antibody is a 兔 多克隆 antibody detecting SNAP23 in WB, IHC, ICC, IF, IHC (fro) 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3044163
发货至: 中国
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Quick Overview for SNAP23 抗体 (C-Term) (ABIN3044163)

抗原

See all SNAP23 抗体
SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SNAP23 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 192-211, C-Term

    原理

    Anti-SNAP23 Antibody

    序列

    DTNRDRIDIA NARAKKLIDS

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-SNAP23 Antibody (ABIN3044163). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human SNAP23, different from the related rat and mouse sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry , 0.5-1 μg/mL, Human, -
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

    别名

    SNAP23

    背景

    Synonyms: Synaptosomal-associated protein 23,SNAP-23,Vesicle-membrane fusion protein SNAP-23,SNAP23,

    Tissue Specificity: Ubiquitous. Highest levels where found in placenta.

    Background: SNAP23 (Synaptosomal-Associated Protein, 23-KD), also called SNAP23A, is a protein that in humans is encoded by the SNAP23 gene. The SNAP23 gene has 8 exons, with the initiation codon located in exon 2. The SNAP23 gene is mapped on 15q15.1-q15.2. The SNAP23 cDNA encodes a 211-amino acid polypeptide with a predicted mass of 23 kD. Its amino acid sequence is 59 % identical to that of SNAP25. Northern blot analysis revealed that SNAP23 is ubiquitously expressed. SNAP23 is able to bind to multiple syntaxins as well as to multiple vesicle-associated membrane proteins. After relocation, SNAP23 is required for exocytosis, implying a crucial role in promoting membrane fusion. TIVAMP-containing vesicles were concentrated in the apical domain of epithelial cells. STX3A and SNAP23 were codistributed at the apical plasma membrane, where they formed N-ethyl maleimide-dependent SNARE complexes with TIVAMP and cellubrevin. SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion.

    Sequence Similarities: Belongs to the SNAP-25 family.

    分子量

    23 kDa

    UniProt

    O00161
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