TRPC6 抗体 (Middle Region)
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北京 101111
Quick Overview for TRPC6 抗体 (Middle Region) (ABIN3044146)
抗原
See all TRPC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 249-265, Middle Region
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原理
- Anti-TRPC6 Antibody
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序列
- HDYFCKCNDC NQKQKHD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-TRPC6 Antibody (ABIN3044146). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human TRPC6, different from the related rat and mouse sequences by three amino acids.
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亚型
- IgG
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anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 1-192) antibody
TRPC6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 500-600) antibodyTRPC6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibodyMicroarray verified TRPC6 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB620777 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 24-38), (Intracellular) antibodyTRPC6 适用: 小鼠 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (AA 573-586), (Extracellular) antibodyKO Validated TRPC6 适用: 大鼠 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibodyVerified TRPC6 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibodyMicroarray verified TRPC6 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB591644 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) antibodyMicroarray verified TRPC6 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB447436 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibodyTRPC6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibodyTRPC6 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3F2-H10-F2 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." in: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).
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: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." in: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).
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- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
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别名
- TRPC6
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背景
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Synonyms: Short transient receptor potential channel 6,TrpC6,Transient receptor protein 6,TRP-6,TRPC6,TRP6,
Tissue Specificity: Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm. .
Background: Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene encoding a protein of the same name. The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily.
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分子量
- 106 kDa
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UniProt
- Q9Y210
抗原
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