SOD3 抗体 (N-Term)
(2 references)Quick Overview for SOD3 抗体 (N-Term) (ABIN3044113)
抗原
See all SOD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-56, N-Term
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原理
- Anti-Superoxide Dismutase 3/SOD3 Antibody Picoband®
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序列
- KVTEIWQEVM QRRDDD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Superoxide Dismutase 3/SOD3 Antibody (ABIN3044113). Tested in IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human SOD3.
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亚型
- IgG
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anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 19-240) antibody
SOD3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 16-244) antibodySOD3 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) antibodySOD3 适用: 人 WB, IHC, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 4GG11G6 unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 19-240) antibodySOD3 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 19-160) antibodySOD3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 7-36) antibodySOD3 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 25-251) antibodySOD3 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 7-36), (N-Term) antibodySOD3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19866 unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (AA 19-160) antibodySOD3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 3, Extracellular (SOD3) (Internal Region) antibodySOD3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human,
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human,
Western blot, 0.1-0.5 μg/mL, Human
1. Folz, R. J., Crapo, J. D.Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene.Genomics 22: 162-171, 1994. 2. Hjalmarsson, K., Marklund, S. L., Engstrom, A., Edlund, T.Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase.Proc. Nat. Acad. Sci. 84: 6340-6344, 1987. 3. Stern, L.F., Chapman, N. H., Wijsman, E. M., Altherr, M. R., Rosen, D. R.Assignment of SOD3 to human chromosome band 4p15.3-p15.1 with somatic cell and radiation hybrid mapping, linkage mapping, and fluorescent in-situ hybridization.Cytogenet. Genome Res. 101: 178 only, 2003. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).
: "Edaravone rescues the lung by inhibiting lipid peroxidation and pro-inflammatory cytokines in a rat model." in: Chinese medical journal, Vol. 127, Issue 5, pp. 968-70, (2014) (PubMed).
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: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).
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- SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))
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别名
- SOD3
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背景
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Synonyms: Extracellular superoxide dismutase [Cu-Zn],EC-SOD,1.15.1.1,SOD3,
Tissue Specificity: Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Background: SOD3 (SUPEROXIDE DISMUTASE 3) also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al. (1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al. (2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is though to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
Sequence Similarities: Belongs to the Cu-Zn superoxide dismutase family.
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分子量
- 60 kDa
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UniProt
- P08294
抗原
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