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SMAD2 抗体 (N-Term)

Name: SMAD2 抗体 (N-Term)
SKU: ABIN3044112
Availability: OutOfStock

Cited in 2+ publications. The 兔多克隆 anti-SMAD2 antibody (ABIN3044112) specifically detects SMAD2 in WB, IHC 和 ICC. The antibody is reactive with 人 samples.

Anti-Smad2 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: SMMC Cell Lysate Lane 4: JURKAT Cell Lysate Lane 5: U87 Cell Lysate Lane 6: MCF-7 Cell Lysate (SMAD2 抗体 (N-Term))

Anti-Smad2 antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (SMAD2 抗体 (N-Term))

IHC

Anti-Smad2 antibody, ICC ICC: HELA Cell (SMAD2 抗体 (N-Term))

IHC

Western Blotting (WB) image for anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibody (ABIN3044112) (SMAD2 抗体 (N-Term))

4 images

(2 references)

产品编号 ABIN3044112

发货至: 中国

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中国
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Quick Overview for SMAD2 抗体 (N-Term) (ABIN3044112)

抗原

See all SMAD2 抗体

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This SMAD2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Discover our top product SMAD2 Primary Antibody

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N-Term

原理

Anti-Smad2 Antibody

序列

DQWDTTGLYS FSEQTRSLD

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

identical to the related rat,mouse sequences.

产品特性

Anti-Smad2 Antibody. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Smad2, identical to the related rat and mouse sequences.

亚型

IgG
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (C-Term) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, Co-IP 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) antibody
SMAD2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer467) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 83-264) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2D7 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer250) antibody
KD Validated SMAD2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4150 unconjugated Recombinant Antibody

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibody
SMAD2 适用: 人 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry , 0.5-1 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Xu, Xu, Saud, Lu, Liu, Fang, Zhang, Hu, Li: "Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 2601830, (2016) (PubMed).

Tao, Hu, Li, Liu, Wu, Li, Fu, Wei, Luo: "Tranilast prevents the progression of chronic cyclosporine nephrotoxicity through regulation of transforming growth factor ?/Smad pathways." in: Transplantation proceedings, Vol. 43, Issue 5, pp. 1985-8, (2011) (PubMed).
抗原

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

别名

SMAD2

背景

Background: Smad2 (Mothers against decapentaplegic homolog 2), also known as MADR2, MADH2, SMAD family member 2 or SMAD2, is a protein that in humans is encoded by the SMAD2 gene. MAD homolog 2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. Eppert et al. (1996) mapped the MADR2 gene close to DPC4 at 18q21, a region which is frequently deleted in colorectal cancers. Riggins et al. (1996) mapped the human MADH2 gene to 18q21. Nakao et al. (1997) refined the localization of the SMAD2 gene to 18q21.1, approximately 3 Mb proximal to DPC4, by fluorescence in situ hybridization. SMAD2 mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors.
Gene Full Name: SMAD family member 2
Sequence Similarities: Belongs to the dwarfin/SMAD family.

分子量

60 kDa

基因ID

4087

UniProt

Q15796

途径

Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus