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IBSP 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects IBSP in WB 和 IHC. It exhibits reactivity toward 小鼠 和 大鼠. It has been mentioned in 2+ publications
产品编号 ABIN3044104
发货至: 中国
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Quick Overview for IBSP 抗体 (C-Term) (ABIN3044104)

抗原

See all IBSP 抗体
IBSP (Integrin-Binding Sialoprotein (IBSP))

适用

  • 54
  • 10
  • 7
  • 2
  • 1
小鼠, 大鼠

宿主

  • 48
  • 4
  • 2
  • 1
  • 1

克隆类型

  • 48
  • 8
多克隆

标记

  • 29
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IBSP antibody is un-conjugated

应用范围

  • 45
  • 20
  • 13
  • 13
  • 10
  • 8
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 9
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Bone Sialoprotein/IBSP Antibody

    序列

    SYYKGHGYEG YEGQNYYYHQ

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by one amino acid.

    产品特性

    Anti-Bone Sialoprotein/IBSP Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bone Sialoprotein, different from the related rat sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Zhou, Deng, Liu, Li: "Effect of kidney-reinforcing and marrow-beneficial Chinese medicine on bone metabolism-related factors following spinal cord injury in rats." in: Experimental and therapeutic medicine, Vol. 12, Issue 1, pp. 485-491, (2016) (PubMed).

    Cheng, Wang, Zhang, Shi: "The osteogenic potential of mesoporous bioglasses/silk and non-mesoporous bioglasses/silk scaffolds in ovariectomized rats: in vitro and in vivo evaluation." in: PLoS ONE, Vol. 8, Issue 11, pp. e81014, (2014) (PubMed).

  • 抗原

    IBSP (Integrin-Binding Sialoprotein (IBSP))

    别名

    IBSP

    背景

    Background: IBSP (integrin-binding sialoprotein) is also known as BSP. The protein encoded by this gene is a major structural protein of the bone matrix. Bone sialoprotein is an acidic glycoprotein of approximately 70 kD that undergoes extensive posttranslational modifications. It constitutes approximately 12 % of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. The BSP gene is mapped to 4q22.1.

    Gene Full Name: integrin binding sialoprotein

    分子量

    18 kDa

    基因ID

    15891

    UniProt

    Q61711
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