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GATA2 抗体 (N-Term)

This anti-GATA2 antibody is a 兔 多克隆 antibody detecting GATA2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3044102
发货至: 中国

Quick Overview for GATA2 抗体 (N-Term) (ABIN3044102)

抗原

See all GATA2 抗体
GATA2 (GATA Binding Protein 2 (GATA2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GATA2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 46-60, N-Term

    原理

    Anti-GATA2 Antibody Picoband®

    序列

    DVFFNHLDSQ GNPYY

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-GATA2 Antibody (ABIN3044102). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human GATA2, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Ciciotte, S. L., Tsai, F.-Y., Peters, L. L.Gata2 maps to mouse chromosome 6.Mammalian Genome 8: 69-70, 1997. 2. Dorfman, D. M., Wilson, D. B., Bruns, G. A., Orkin, S. H.Human transcription factor GATA-2: evidence for regulation of preproendothelin-1 gene expression in endothelial cells.J. Biol. Chem. 267: 1279-1285, 1992. 3. Wieser, R., Volz, A., Vinatzer, U., Gardiner, K., Jager, U., Mitterbauer, M., Ziegler, A., Fonatsch, C.Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia.Biochem. Biophys. Res. Commun. 273: 239-245, 2000.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GATA2 (GATA Binding Protein 2 (GATA2))

    别名

    GATA2

    背景

    Synonyms: Endothelial transcription factor GATA-2,GATA-binding protein 2,GATA2,

    Tissue Specificity: Endothelial cells.

    Background: GATA2 (GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al. (1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al. (1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al. (2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

    Sequence Similarities: Contains 2 GATA-type zinc fingers.

    分子量

    95 kDa

    UniProt

    P23769

    途径

    Stem Cell Maintenance
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