HYAL3 抗体 (C-Term)
Quick Overview for HYAL3 抗体 (C-Term) (ABIN3044086)
抗原
See all HYAL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 357-371, C-Term
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原理
- Anti-Hyaluronidase-3 HYAL3 Antibody Picoband®
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序列
- SHQRCHGHGR CARRD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Hyaluronidase-3 HYAL3 Antibody (ABIN3044086). Tested in IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL3, different from the related rat sequence by three amino acids, and different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Hyaluronidase-3 (HYAL3) antibody
HYAL3 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-3 (HYAL3) (AA 1-417) antibodyHYAL3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-3 (HYAL3) (AA 198-417) antibodyHYAL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-3 (HYAL3) (AA 198-417) antibodyHYAL3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-3 (HYAL3) (AA 1-417) antibodyHYAL3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hyaluronidase-3 (HYAL3) (C-Term) antibodyHYAL3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-3 (HYAL3) (C-Term) antibodyHYAL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. Csoka, A. B., Scherer, S. W., Stern, R. Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31.Genomics 60: 356-361, 1999. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HYAL3 (Hyaluronidase-3 (HYAL3))
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别名
- HYAL3
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背景
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Synonyms: Hyaluronidase-3;Hyal-3;3.2.1.35;Hyaluronoglucosaminidase-3;Lung carcinoma protein 3;LuCa-3;HYAL3;LUCA3;
Tissue Specificity: Bone marrow, testis and kidney. Isoform 4 is detected in all bladder tumor and prostate tumor cells. .
Background: HYAL3 (hyaluronoglucosaminidase 3) is an enzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, Minna14. By Northern blot analysis, expression of a 2.1-kb HYAL3 transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.
Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.
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分子量
- 93 kDa
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UniProt
- O43820
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途径
- Glycosaminoglycan Metabolic Process
抗原
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