Coxsackie Adenovirus Receptor 抗体 (C-Term)
Quick Overview for Coxsackie Adenovirus Receptor 抗体 (C-Term) (ABIN3044083)
抗原
See all Coxsackie Adenovirus Receptor (CXADR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 313-328, C-Term
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原理
- Anti-Coxsackie Adenovirus Receptor/CXADR Antibody Picoband®
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序列
- YSKTQYNQVP SEDFER
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Coxsackie Adenovirus Receptor/CXADR Antibody (ABIN3044083). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Coxsackie Adenovirus Receptor, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (AA 20-229) antibody
CXADR 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (AA 1-365) antibodyCXADR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) antibodyCXADR 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (AA 132-161) antibodyCXADR 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB17619 unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (N-Term) antibodyCXADR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (AA 259-365) antibodyCXADR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) antibodyCXADR 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (AA 1-365) antibodyCXADR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Coxsackie Virus and Adenovirus Receptor (CXADR) (N-Term) antibodyCXADR 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Tomko, R. P., Xu, R., Philipson, L.HCAR and MCAR: the human and mouse receptors for subgroup C adenoviruses and group B coxsackieviruses.Proc. Nat. Acad. Sci. 94: 3352-3356, 1997. 2. Witherden, D. A., Verdino, P., Rieder, S. E., Garijo, O., Mills, R. E., Teyton, L., Fischer, W. H., Wilson, I. A., Havran, W. L. The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gamma-delta T cell activation. Science 329: 1205-1210, 2010. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))
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别名
- CXADR
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背景
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Synonyms: Coxsackievirus and adenovirus receptor,CAR,hCAR,CVB3-binding protein,Coxsackievirus B-adenovirus receptor,HCVADR,CXADR,CAR,
Tissue Specificity: Expressed in pancreas, brain, heart, small intestine, testis, prostate and at a lower level in liver and lung. Isoform 5 is ubiquitously expressed. Isoform 3 is expressed in heart, lung and pancreas. In skeletal muscle, isoform 1 is found at the neuromuscular junction and isoform 2 is found in blood vessels. In cardiac muscle, isoform 1 and isoform 2 are found at intercalated disks. In heart expressed in subendothelial layers of the vessel wall but not in the luminal endothelial surface. Expression is elevated in hearts with dilated cardiomyopathy. .
Background: CXADR (Coxsackie virus and adenovirus receptor) is a protein that in humans is encoded by the CXADR gene, also known as CAR,CVB3-binding protein, Coxsackievirus B-adenovirus receptor. The CAR cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis, they detected highest expression of 1.4-kb and 6-kb CXADR transcripts in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse Cxadr showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.
Sequence Similarities: Belongs to the peptidase C14A family.
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分子量
- 50 kDa
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UniProt
- P78310
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途径
- Cell-Cell Junction Organization
抗原
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