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CD1d 抗体 (N-Term)

CD1D 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044081
发货至: 中国
  • 抗原 See all CD1d (CD1D) 抗体
    CD1d (CD1D) (CD1d Molecule (CD1D))
    抗原表位
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 76-92, N-Term
    适用
    • 56
    • 34
    • 16
    • 4
    宿主
    • 58
    • 15
    • 11
    克隆类型
    • 60
    • 24
    多克隆
    标记
    • 36
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD1d antibody is un-conjugated
    应用范围
    • 40
    • 35
    • 21
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Antigen-presenting glycoprotein CD1d(CD1D) detection. Tested with WB, IHC-P in Human.
    序列
    FSDQQWETLQ HIFRVYR
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Antigen-presenting glycoprotein CD1d(CD1D) detection. Tested with WB, IHC-P in Human.
    Gene Name: CD1d molecule
    Protein Name: Antigen-presenting glycoprotein CD1d
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human CD1d(76-92aa FSDQQWETLQHIFRVYR).
    亚型
    IgG
    Top Product
    Discover our top product CD1D Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD1D is approximately 2.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    CD1d (CD1D) (CD1d Molecule (CD1D))
    别名
    CD1D (CD1D 产品)
    别名
    CD1A antibody, R3 antibody, CD1D antibody, CD1D1 antibody, CD1d molecule antibody, CD1D antigen, d polypeptide antibody, CD1D antibody
    背景
    CD1D(CD1d molecule) also known as R3G1, Antigen-presenting glycoprotein CD1d, R3G1, CD1D, is the sole group-2 member of the CD1 family of major histocompatibility(MHC)-like glycoproteins. Expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. It is the only member of the group 2 CD1 Molecules. CD1d presented lipid antigens activate a special class of T cells, known as Natural Killer T(NKT) cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production. Jayawardena-Wolf et al. described 2 different pathways of Cd1d trafficking to endosomal compartments in mouse cells. A tyrosine-based motif governs recycling between the plasma membrane and the endosome, while Cd1d associates, like major histocompatibility complex class II antigens, with the invariant chain, or II, in the endoplasmic reticulum. Both pathways enhance antigen presentation to Cd1d-restricted natural killer T cells.

    Synonyms: Antigen-presenting glycoprotein CD1d antibody|CD1.1 antibody|CD1A antibody|CD1d antibody|CD1D antigen antibody|CD1D antigen d polypeptide antibody|CD1d molecule antibody|CD1D_HUMAN antibody|Cd1d1 antibody|Differentiation antigen CD1 alpha 3 antibody|HMC class I antigen like glycoprotein CD1D antibody|Ly 38 antibody|MGC34622 antibody|R3 antibody|R3G1 antibody|T cell surface glycoprotein CD1d antibody|T cell surface glycoprotein CD1d precursor antibody|Thymocyte antigen CD1D antibody
    UniProt
    P15813
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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