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- 抗原 See all CD1d (CD1D) 抗体
- CD1d (CD1D) (CD1d Molecule (CD1D))
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抗原表位
- AA 76-92, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD1d antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-CD1d Antibody Picoband®
- 序列
- FSDQQWETLQ HIFRVYR
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-CD1d Antibody (ABIN3044081). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human CD1d.
- 亚型
- IgG
- Top Product
- Discover our top product CD1D Primary Antibody
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anti-CD1d Molecule (CD1D) (AA 56-271) antibody
CD1D 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) (AA 32-302) antibodyCD1D 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibodyCD1D 适用: 小鼠, 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibody (PE)CD1D 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 51-1 PE
anti-CD1d Molecule (CD1D) (AA 20-190) antibodyCD1D 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibodyCD1D 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) (AA 1-335) antibodyCD1D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) (Internal Region) antibodyCD1D 适用: 小鼠, 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD1d Molecule (CD1D) antibodyCD1D 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 51-1 unconjugated
anti-CD1d Molecule (CD1D) (AA 64-298) antibodyCD1D 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Jayawardena-Wolf, J., Benlagha, K., Chiu, Y.-H., Mehr, R., Bendelac, A. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain.Immunity 15: 897-908, 2001. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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- 抗原
- CD1d (CD1D) (CD1d Molecule (CD1D))
- 别名
- CD1D (CD1D 产品)
- 背景
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Synonyms: Antigen-presenting glycoprotein CD1d;R3G1;CD1d;CD1D;
Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Background: CD1D (CD1d molecule) also known as R3G1, Antigen-presenting glycoprotein CD1d, R3G1, CD1D, is the sole group-2 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins. Expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. It is the only member of the group 2 CD1 molecules. CD1d presented lipid antigens activate a special class of T cells, known as Natural Killer T (NKT) cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production. Jayawardena-Wolf et al. described 2 different pathways of Cd1d trafficking to endosomal compartments in mouse cells. A tyrosine-based motif governs recycling between the plasma membrane and the endosome, while Cd1d associates, like major histocompatibility complex class II antigens, with the invariant chain, or II, in the endoplasmic reticulum. Both pathways enhance antigen presentation to Cd1d-restricted natural killer T cells.
Sequence Similarities: Belongs to the peptidase C14A family.
- 分子量
- 31 kDa
- UniProt
- P15813
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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