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ADAM19 抗体 (N-Term)

Adam19 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044069
发货至: 中国
  • 抗原 See all ADAM19 (Adam19) 抗体
    ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))
    抗原表位
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 286-298, N-Term
    适用
    • 39
    • 11
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 37
    • 1
    • 1
    • 1
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM19 antibody is un-conjugated
    应用范围
    • 33
    • 12
    • 12
    • 10
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    原理
    Anti-ADAM19 Antibody Picoband®
    序列
    RRKLLAQKYH DNA
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-ADAM19 Antibody (ABIN3044069). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product Adam19 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human
    1. Hirohata, S., Seldin, M. F., Apte, S. S. Chromosomal assignment of two ADAM genes, TACE (ADAM17) and MLTNB (ADAM19), to human chromosomes 2 and 5, respectively, and of Mltnb to mouse chromosome 11. Genomics 54: 178-179, 1998. 2. Inoue, D., Reid, M., Lum, L., Kratzschmar, J., Weskamp, G., Myung, Y. M., Baron, R., Blobel, C. P. Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells. J. Biol. Chem. 273: 4180-4187, 1998.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))
    别名
    ADAM19 (Adam19 产品)
    背景

    Synonyms: Disintegrin and metalloproteinase domain-containing protein 19,ADAM 19,3.4.24.-,Meltrin-beta,Metalloprotease and disintegrin dendritic antigen marker,MADDAM,ADAM19,MLTNB,FKSG34,

    Tissue Specificity: Expressed in many normal organ tissues and several cancer cell lines.

    Background: ADAM19 (A Disintegrin and Metalloproteinase Domain 19), also known as MLTNB, is a human gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Hirohata et al. (1998) used radiation hybrids to map ADAM19 to mouse chromosome 11 and to human chromosome 5q32-q33.

    Sequence Similarities: Contains 1 disintegrin domain.

    分子量
    105 kDa
    UniProt
    Q9H013
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