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- 抗原 See all 2B4 (CD244) 抗体
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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抗原表位
- AA 357-370, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This 2B4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Natural killer cell receptor 2B4(CD244) detection. Tested with WB, IHC-P in Human.
- 序列
- RLSRKELENF DVYS
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Natural killer cell receptor 2B4(CD244) detection. Tested with WB, IHC-P in Human.
Gene Name: CD244 Molecule, natural killer cell receptor 2B4
Protein Name: Natural killer cell receptor 2B4 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CD244(357-370aa RLSRKELENFDVYS).
- 亚型
- IgG
- Top Product
- Discover our top product CD244 Primary Antibody
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anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 20-221) antibody
CD244 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 22-221) antibodyCD244 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM69 unconjugated Recombinant Antibody
anti-Natural Killer Cell Receptor 2B4 (CD244) (N-Term) antibodyCD244 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 151-250) antibodyCD244 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (pTyr271) antibodyCD244 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 26-212) antibodyCD244 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 22-224) antibodyCD244 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) antibodyCD244 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 1-365) antibodyCD244 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Natural Killer Cell Receptor 2B4 (CD244) (AA 22-224) antibodyCD244 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- 别名
- CD244 (CD244 产品)
- 别名
- CD244 antibody, 2B4 antibody, NAIL antibody, NKR2B4 antibody, Nmrk antibody, SLAMF4 antibody, C9.1 antibody, F730046O15Rik antibody, Ly90 antibody, CD244 molecule antibody, CD244 natural killer cell receptor 2B4 antibody, CD244 antibody, Cd244 antibody
- 背景
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CD244(Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. Tangye et al.(1999) mapped the 2B4 gene to 1q22. Suzuki et al.(2008) identified a functional single-nucleotide polymorphism(SNP) in the CD244 gene that contributes to rheumatoid arthritis susceptibility. Functional analysis by Boles et al.(1999) demonstrated that engagement of 2B4 with specific antibody activates NK cytolytic activity. Using recombinant human NK cell-activating ligand 2B4 fused to domains 3 and 4 of rodent Cd4 and flow cytometric analysis, Brown et al.(1998) demonstrated that CD48 binds to 2B4. Watzl et al.(2000) showed that antibody-mediated cross-linking of 2B4 leads to its rapid tyrosine phosphorylation, which is necessary for 2B4-mediated killer cell activity.
Synonyms: 2B4 antibody|C9.1 antibody|CD244 antibody|CD244 antigen antibody|CD244 Molecule natural killer cell receptor 2B4 antibody|CD244 natural killer cell receptor 2B4 antibody|CD244_HUMAN antibody|F730046O15Rik antibody|h2B4 antibody|Ly90 antibody|NAIL antibody|Natural killer cell activation-inducing ligand antibody|Natural killer cell receptor 2B4 antibody|NK cell activation inducing ligand antibody|NK cell activation inducing ligand NAIL antibody|NK cell activation-inducing ligand antibody|NK cell type I receptor protein 2B4 antibody|NKR2B4 antibody|Nmrk antibody|Non-MHC restricted killing associated antibody|OTTHUMP00000027884 antibody|p38 antibody|SLAM family, member 4 antibody|SLAMF4 antibody
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