RGS3 抗体 (C-Term)
Quick Overview for RGS3 抗体 (C-Term) (ABIN3044065)
抗原
See all RGS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 909-925, C-Term
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原理
- Anti-RGS3 Antibody Picoband®
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序列
- DSYTREHTKE NLQSITR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-RGS3 Antibody (ABIN3044065). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse RGS3, identical to the related rat sequence, and different from the related human sequence by two amino acids.
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 3 (RGS3) (AA 1-192) antibody
RGS3 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1E8-C7 unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (AA 1-193) antibodyRGS3 适用: 人 WB, IHC, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1E8-C7 unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (C-Term) antibodyRGS3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (AA 273-307) antibodyRGS3 适用: 人 WB 宿主: 兔 Polyclonal RB53399 unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (AA 1-168) antibodyRGS3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (AA 1-168) antibodyRGS3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (C-Term) antibodyRGS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (C-Term) antibodyRGS3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (AA 1-261) antibodyRGS3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 3 (RGS3) (C-Term) antibodyRGS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Chatterjee, T. K., Eapen, A., Kanis, A. B., Fisher, R. A. Genomic organization, 5-prime-flanking region, and chromosomal localization of the human RGS3 gene. Genomics 45: 429-433, 1997. 2. Druey, K. M., Blumer, K. J., Kang, V. H., Kehrl, J. H. Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature 379: 742-746, 1996. 3. Lu, Q., Sun, E. E., Klein, R. S., Flanagan, J. G. Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell 105: 69-79, 2001. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- RGS3 (Regulator of G-Protein Signaling 3 (RGS3))
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别名
- Rgs3
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背景
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Synonyms: Regulator of G-protein signaling 3,RGS3,C2PA,Rgs3,
Tissue Specificity: Detected in embryos from E8.5-16.5 in cortical ventricular zone, dorsal root ganglia and cerebellar primordia. Isoform 3 is detected in testis and in spermatocytes from newborn mice. Levels increase and reach a maximum after 21 days, after this they decrease again. Long isoforms are widely expressed. .
Background: RGS3 (Regulator of G Protein Signaling 3), is a protein that in humans is encoded by the RGS3 gene. Chatterjee et al. (1997) studied RGS3, the largest member of the RGS family then identified. Mouse Pdz-Rgs3 can mediate signaling from the ephrin-B cytoplasmic tail. By radiation hybrid mapping, Chatterjee et al. (1997) assigned the RGS3 gene to chromosome 9q31-q33. Lu et al. (2001) showed that Sdf1, a chemokine with a G protein-coupled receptor, and Bdnf are chemoattractants for cerebellar granule cells, and that Sdf1 chemoattraction is selectively inhibited by soluble ephrin-B receptor. This inhibition could be blocked by a truncated Pdz-Rgs3 protein lacking the RGS domain.
Sequence Similarities: Contains 1 PDZ (DHR) domain.
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分子量
- 93 kDa
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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