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TRAF4 抗体 (C-Term)

TRAF4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044048
发货至: 中国
  • 抗原 See all TRAF4 抗体
    TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
    抗原表位
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 437-454, C-Term
    适用
    • 48
    • 18
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 3
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 29
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This TRAF4 antibody is un-conjugated
    应用范围
    • 31
    • 17
    • 6
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-TRAF4 Antibody Picoband®
    序列
    PKFISHQDIR KRNYVRDD
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-TRAF4 Antibody (ABIN3044048). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human TRAF4, identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product TRAF4 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Regnier, C. H., Masson, R., Kedinger, V., Textoris, J., Stoll, I., Chenard, M.-P., Dierich, A., Tomasetto, C., Rio, M.-C. Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice. Proc. Nat. Acad. Sci. 99: 5585-5590, 2002. Note: Erratum: Proc. Nat. Acad. Sci. 99: 8457 only, 2002. 2. Regnier, C. H., Tomasetto, C., Moog-Lutz, C., Chenard, M.-P., Wendling, C., Basset, P., Rio, M.-C. Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma. J. Biol. Chem. 270: 25715-25721, 1995. 3. Tomasetto, C., Regnier, C., Moog-Lutz, C., Mattei, M. G., Chenard, M. P., Lidereau, R., Basset, P., Rio, M. C. Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. Genomics 28: 367-376, 1995.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
    别名
    TRAF4 (TRAF4 产品)
    背景

    Synonyms: TNF receptor-associated factor 4,Cysteine-rich domain associated with RING and Traf domains protein 1,Metastatic lymph node gene 62 protein,MLN 62,RING finger protein 83,TRAF4,CART1, MLN62, RNF83,

    Tissue Specificity: Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. .

    Background: TRAF4 (TNF Receptor-Associated Factor 4), also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF3 gene. TRAF4 is a member of the TNF receptor associated factor (TRAF) family, a family of scaffold proteins. Tomasetto et al. (1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes. The TRAF4 cDNA, which they designated MLN62, was mapped to 17q11-q12 by radioisotopic in situ hybridization. To investigate the biologic function of TRAF4, Regnier et al. (2002) generated Traf4-deficient mice by gene disruption.

    Sequence Similarities: Belongs to the TNF receptor-associated factor family. B subfamily.

    分子量
    56 kDa
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