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TRAF4 抗体 (C-Term)

This anti-TRAF4 antibody is a 兔 多克隆 antibody detecting TRAF4 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3044048
发货至: 中国

Quick Overview for TRAF4 抗体 (C-Term) (ABIN3044048)

抗原

See all TRAF4 抗体
TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TRAF4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 437-454, C-Term

    原理

    Anti-TRAF4 Antibody Picoband®

    序列

    PKFISHQDIR KRNYVRDD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-TRAF4 Antibody (ABIN3044048). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TRAF4, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Regnier, C. H., Masson, R., Kedinger, V., Textoris, J., Stoll, I., Chenard, M.-P., Dierich, A., Tomasetto, C., Rio, M.-C. Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice. Proc. Nat. Acad. Sci. 99: 5585-5590, 2002. Note: Erratum: Proc. Nat. Acad. Sci. 99: 8457 only, 2002. 2. Regnier, C. H., Tomasetto, C., Moog-Lutz, C., Chenard, M.-P., Wendling, C., Basset, P., Rio, M.-C. Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma. J. Biol. Chem. 270: 25715-25721, 1995. 3. Tomasetto, C., Regnier, C., Moog-Lutz, C., Mattei, M. G., Chenard, M. P., Lidereau, R., Basset, P., Rio, M. C. Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. Genomics 28: 367-376, 1995.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

    别名

    TRAF4

    背景

    Synonyms: TNF receptor-associated factor 4,Cysteine-rich domain associated with RING and Traf domains protein 1,Metastatic lymph node gene 62 protein,MLN 62,RING finger protein 83,TRAF4,CART1, MLN62, RNF83,

    Tissue Specificity: Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. .

    Background: TRAF4 (TNF Receptor-Associated Factor 4), also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF3 gene. TRAF4 is a member of the TNF receptor associated factor (TRAF) family, a family of scaffold proteins. Tomasetto et al. (1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes. The TRAF4 cDNA, which they designated MLN62, was mapped to 17q11-q12 by radioisotopic in situ hybridization. To investigate the biologic function of TRAF4, Regnier et al. (2002) generated Traf4-deficient mice by gene disruption.

    Sequence Similarities: Belongs to the TNF receptor-associated factor family. B subfamily.

    分子量

    56 kDa
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