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TJP3 抗体 (C-Term)

The 兔 多克隆 anti-TJP3 antibody (ABIN3044037) specifically detects TJP3 in WB 和 IHC. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN3044037
发货至: 中国
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Quick Overview for TJP3 抗体 (C-Term) (ABIN3044037)

抗原

See all TJP3 抗体
TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

适用

  • 24
  • 7
  • 4
  • 2
  • 1
小鼠, 大鼠

宿主

  • 27
  • 2

克隆类型

  • 28
  • 1
多克隆

标记

  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
This TJP3 antibody is un-conjugated

应用范围

  • 28
  • 13
  • 9
  • 9
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Zonula occludens protein 3/TJP3 Antibody

    序列

    RARDVESSDD EGYDWGPATD L

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat sequence.

    产品特性

    Anti-Zonula occludens protein 3/TJP3 Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Zonula occludens protein 3, identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Rat, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

    别名

    TJP3

    背景

    Background: TJP3 (TIGHT JUNCTION PROTEIN 3), also called ZO3, is a protein that in humans is encoded by the TJP3 gene. TJP3 is a member of the family of membrane-associated guanylate kinase-like proteins (MAGUK) that associate with intracellular junctions (Itoh et al., 1999). Haskins et al. (1998) showed that recombinant Tjp3 binds in vitro translated Tjp1 and binds ly to the cytoplasmic tail of occludin but no binding was detected between Tjp3 and Tjp2. Roh et al. (2002) determined that Tjp3 interacted with PATJ (INADL) and that both proteins colocalized to tight junctions in vivo. In vitro studies showed that the sixth and eighth PDZ domains of PATJ mediated interaction with the Tjp3 C-terminal domain and with Cldn1, respectively.

    Gene Full Name: tight junction protein 3

    Sequence Similarities: Belongs to the MAGUK family.

    分子量

    150 kDa

    基因ID

    27375

    UniProt

    Q9QXY1
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