Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) (AA 647-666), (C-Term) 抗体
Our Local Distributor
北京 101111
Quick Overview for Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) (AA 647-666), (C-Term) 抗体 (ABIN3044029)
抗原
See all Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 647-666, C-Term
-
原理
- Anti-RIAM/APBB1IP Antibody
-
序列
- EQDFMSDLMK ALQKKRGNVS
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-RIAM/APBB1IP Antibody (ABIN3044029). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human APBB1IP, different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat
Immunocytochemistry , 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 Interacting Protein (APBB1IP)
-
别名
- APBB1IP
-
背景
-
Synonyms: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein,APBB1-interacting protein 1,Proline-rich EVH1 ligand 1,PREL-1,Proline-rich protein 73,Rap1-GTP-interacting adapter molecule,RIAM,Retinoic acid-responsive proline-rich protein 1,RARP-1,APBB1IP,PREL1, RARP1, RIAM,
Tissue Specificity: Widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes. .
Background: APBB1IP (APBB1-Interacting Protein), also called RIAM or RARP1, is a protein that in humans is encoded by the APBB1IP gene. By genomic sequence analysis, Lafuente et al. (2004) mapped the RIAM gene to chromosome 10p12.1. Using promoter-< a href="https://www.bosterbio.com/cells/reporter-cell-lines" style="color:#ea8d28">reporter gene assays, Inagaki et al. (2003) found that RARP1 suppressed transcription from AP1 and SRE sites, but not CRE sites, in all cell lines examined. The proline-rich regions of RARP1 suppressed AP1 transactivation. Lafuente et al. (2004) found that RIAM interacted with profilin and VASP, molecules that regulate actin dynamics, as well as with RAP1-GTP.
Sequence Similarities: Belongs to the MRL family.
-
分子量
- 110-120 kDa
-
UniProt
- Q7Z5R6
抗原
-