POR 抗体 (C-Term)
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- 抗原 See all POR 抗体
- POR (P450 (Cytochrome) Oxidoreductase (POR))
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抗原表位
- AA 659-677, C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- Anti-Cytochrome P450 Reductase/POR Antibody Picoband®
- 序列
- DYIKKLMTKG RYSLDVWS
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-Cytochrome Reductase/POR Antibody (ABIN3044023). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human POR, different from the related rat and mouse sequences by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product POR Primary Antibody
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anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 77-518) antibody
POR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-250) antibodyPOR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (N-Term) antibodyKO Validated POR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 2-671) antibodyPOR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyKO Validated POR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 633-668), (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry, 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Adachi, M., Asakura, Y., Matsuo, M., Yamamoto, T., Hanaki, K., Arlt, W. POR R457H is a global founder mutation causing Antley-Bixler syndrome with autosomal recessive trait. (Letter) Am. J. Med. Genet. 140A: 633-635, 2006. 2. Miller, W. L. Congenital adrenal hyperplasia. (Letter) New Eng. J. Med. 314: 1321-1322, 1986. 3. Shephard, E. A., Phillips, I. R., Santisteban, I., West, L. F., Palmer, C. N., Ashworth, A., Povey, S. Isolation of a human cytochrome P-450 reductase cDNA clone and localization of the corresponding gene to chromosome 7q11.2. Ann. Hum. Genet. 53: 291-301, 1989. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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- 抗原
- POR (P450 (Cytochrome) Oxidoreductase (POR))
- 别名
- POR (POR 产品)
- 背景
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Synonyms: NADPH--cytochrome P450 reductase,CPR,P450R,1.6.2.4,POR,CYPOR,
Tissue Specificity: Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Isoform Long predominates in all tissues examined. Isoform Delta12 is detected only in trachea. Isoform Delta14-15 is only detected in lung. Isoform Delta14 is detected in all tissues examined with the strongest expression in heart. Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U-937 histiocytic lymphoma cell lines (at protein level). .
Background: POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons ly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Sequence Similarities: In the C-terminal section, belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
- 分子量
- 120 kDa
- UniProt
- P16435
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
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