MFGE8 抗体 (Middle Region)
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北京 101111
Quick Overview for MFGE8 抗体 (Middle Region) (ABIN3044017)
抗原
See all MFGE8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Milk Fat Globule 1/MFGE8 Antibody
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序列
- NGHEFDFIHD VNKKHK
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Milk Fat Globule 1/MFGE8 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Human Milk Fat Globule 1.
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亚型
- IgG
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anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 1-200) antibody
MFGE8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyMFGE8 适用: 人 IHC 宿主: 小鼠 Monoclonal MFG-06 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyMFGE8 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 73-421) antibodyMFGE8 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 159-417) antibodyMFGE8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyMFGE8 适用: 人 IHC, FACS, IF 宿主: 小鼠 Monoclonal EDM45 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) antibodyCarrier-free MFGE8 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal MFG-06 unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 1-387) antibodyMFGE8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 1-387) antibodyMFGE8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 61-170) antibodyMFGE8 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1E7 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants." in: Journal of the Pediatric Infectious Diseases Society, Vol. 6, Issue 1, pp. 87-90, (2018) (PubMed).
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- MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
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别名
- MFGE8
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背景
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Background: MFGE8 (Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al. (1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al. (2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al. (2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon (PRKCE)-dependent mechanism.
Gene Full Name: milk fat globule EGF and factor V/VIII domain containing
Sequence Similarities: Contains 1 EGF-like domain.
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分子量
- 43 kDa
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基因ID
- 4240
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UniProt
- Q08431
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途径
- SARS-CoV-2 Protein Interactome
抗原
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