ADRA2A 抗体 (Middle Region)
Quick Overview for ADRA2A 抗体 (Middle Region) (ABIN3044006)
抗原
See all ADRA2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 213-228, Middle Region
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原理
- Anti-alpha 2a Adrenergic Receptor/ADRA2A Antibody Picoband®
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序列
- ILVYVRIYQI AKRRTR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-alpha 2a Adrenergic Receptor/ADRA2A Antibody (ABIN3044006). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human alpha 2a Adrenergic Receptor, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 385-450) antibody
ADRA2A 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (Internal Region) antibodyADRA2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 240-380) antibodyADRA2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 7-20), (Extracellular) antibodyADRA2A 适用: 大鼠 WB, IF, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (Internal Region) antibodyVerified ADRA2A 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 331-380) antibodyADRA2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (C-Term) antibodyADRA2A 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 218-374) antibodyADRA2A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 118-152) antibodyADRA2A 适用: 人 WB 宿主: 兔 Polyclonal RB53330 unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 223-256) antibodyADRA2A 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52053 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Philipp, M., Brede, M. E., Hadamek, K., Gessler, M., Lohse, M. J., Hein, L. Placental alpha-2-adrenoceptors control vascular development at the interface between mother and embryo. Nature Genet. 31: 311-315, 2002. 2. Rosengren, A. H., Jokubka, R., Tojjar, D., Granhall, C., Hansson, O., Li, D.-Q., Nagaraj, V., Reinbothe, T. M., Tuncel, J., Eliasson, L., Groop, L., Rorsman, P., Salehi, A., Lyssenko, V., Luthman, H., Renstrom, E. Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes. Science 327: 217-220, 2010. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
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别名
- ADRA2A
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背景
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Synonyms: Alpha-2A adrenergic receptor,Alpha-2 adrenergic receptor subtype C10,Alpha-2A adrenoreceptor,Alpha-2A adrenoceptor,Alpha-2AAR,ADRA2A,ADRA2R, ADRAR,
Background: The alpha-2A adrenergic receptor, also known as ADRA2A denotes the human gene encoding it. This gene is mapped to 10q25.2. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.
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分子量
- 150 kDa
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UniProt
- P08913
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途径
- EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity
抗原
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