EGR1 抗体 (N-Term)
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北京 101111
Quick Overview for EGR1 抗体 (N-Term) (ABIN3043997)
抗原
See all EGR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-43, N-Term
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原理
- Anti-Egr1 Antibody
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序列
- FPHSPTMDNY PKLEEMMLLS N
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Egr1 Antibody (ABIN3043997). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Egr1, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6E8 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibodyEGR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 9-37) antibodyEGR1 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (N-Term) antibodyEGR1 适用: 人, 小鼠, 大鼠, 马, Cow, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 9-37), (N-Term) antibodyEGR1 适用: 人, 小鼠 WB, IF, FACS 宿主: 兔 Polyclonal RB19179 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 401-453) antibodyEGR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 282-433) antibodyEGR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 1-250) antibodyEGR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibodyEGR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 211-320) antibodyEGR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).
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: "ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).
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- EGR1 (Early Growth Response 1 (EGR1))
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别名
- EGR1
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背景
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Synonyms: Early growth response protein 1,EGR-1,AT225,Nerve growth factor-induced protein A,NGFI-A,Transcription factor ETR103,Transcription factor Zif268,Zinc finger protein 225,Zinc finger protein Krox-24,EGR1,KROX24, ZNF225,
Tissue Specificity: In eosinophils as well as trace amounts in neutrophils and monocytes.
Background: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.
Sequence Similarities: Belongs to the EGR C2H2-type zinc-finger protein family.
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分子量
- 58 kDa
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UniProt
- P18146
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途径
- Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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