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EGR1 抗体 (N-Term)

Name: EGR1 抗体 (N-Term)
SKU: ABIN3043997
Availability: OutOfStock

This anti-EGR1 antibody is a 兔多克隆 antibody detecting EGR1 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Anti-Egr1 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: MCF-7 Cell Lysate Lane 4: COLO320 Cell Lysate (EGR1 抗体 (N-Term))

Anti-Egr1 antibody, IHC(P) IHC(P): Rat Intestine Tissue (EGR1 抗体 (N-Term))

IHC

Anti-Egr1 antibody, IHC(F) IHC(F): Rat Intestine Tissue (EGR1 抗体 (N-Term))

IHC

Anti-Egr1 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue (EGR1 抗体 (N-Term))

IHC

Anti-Egr1 antibody, ICC ICC: MCF-7 Cell (EGR1 抗体 (N-Term))

IHC

5 images

(1 reference)

产品编号 ABIN3043997

发货至: 中国

Quick Overview for EGR1 抗体 (N-Term) (ABIN3043997)

抗原

See all EGR1 抗体

EGR1 (Early Growth Response 1 (EGR1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This EGR1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product EGR1 Primary Antibody

抗原表位
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AA 23-43, N-Term

原理

Anti-Egr1 Antibody Picoband®

序列

FPHSPTMDNY PKLEEMMLLS N

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Egr1 Antibody (ABIN3043997). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Egr1, identical to the related rat and mouse sequences.

亚型

IgG
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6E8 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 9-37) antibody
EGR1 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (N-Term) antibody
EGR1 适用: 人, 小鼠, 大鼠, 马, Cow, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 9-37), (N-Term) antibody
EGR1 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB19179 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 401-453) antibody
EGR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 282-433) antibody
EGR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 211-320) antibody
EGR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 444-544) antibody
EGR1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E8 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Das, A., Chendil, D., Dey, S., Mohiuddin, M., Mohiuddin, M., Milbrandt, J., Rangnekar, V. M., Ahmed, M. M. Ionizing radiation down-regulates p53 protein in primary Egr-1(-/-) mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J. Biol. Chem. 276: 3279-3286, 2001. 2. Joslin, J. M., Fernald, A. A., Tennant, T. R., Davis, E. M., Kogan, S. C., Anastasi, J., Crispino, J. D., Le Beau, M. M. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood 110: 719-726, 2007.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Lin, Fang, Cai, Huang, Zhang, Lu, Zhang, Wei: "ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).
抗原

EGR1 (Early Growth Response 1 (EGR1))

别名

EGR1

背景

Synonyms: Early growth response protein 1,EGR-1,AT225,Nerve growth factor-induced protein A,NGFI-A,Transcription factor ETR103,Transcription factor Zif268,Zinc finger protein 225,Zinc finger protein Krox-24,EGR1,KROX24, ZNF225,
Tissue Specificity: In eosinophils as well as trace amounts in neutrophils and monocytes.
Background: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.
Sequence Similarities: Belongs to the EGR C2H2-type zinc-finger protein family.

分子量

58 kDa

UniProt

P18146

途径

Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity