WASP 抗体 (C-Term)
Quick Overview for WASP 抗体 (C-Term) (ABIN3043961)
抗原
See all WASP (WAS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 129-156, C-Term
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原理
- Anti-WASP Antibody Picoband®
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序列
- ADEDEAQAFR ALVQEKIQKR NQRQSGDR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-WASP Antibody Picoband® (ABIN3043961). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human WASP, different from the related mouse sequence by two amino acids.
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亚型
- IgG
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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 57-170) antibody
WAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7B10E4 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 39-251) antibodyWAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) antibodyWAS 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyVerified WAS 适用: 人 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 145-265) antibodyWAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyWAS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 60-250) antibodyWAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 116-144) antibodyWAS 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23643 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 122-152), (Middle Region) antibodyWAS 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 101-200) antibodyWAS 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunocytochemistry , 0.5-1 μg/mL, Human, -
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Jin, Y., Mazza, C., Christie, J., Giliani, S., Fiorini, M., Mella, P., Gandellini, F., Stewart, D., Zhu, Q., Nelson, D. L., Notarangelo, L. D., Ochs, H. D. (2004). "Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation". Blood104 (13): 4010-4019. 2. Radl, J., Dooren, L. H., Morell, A., Skvaril, F., Vossen, J. M., Uittenbogaart, C. H. (1976). "Immunoglobulins and transient paraproteins in sera of patients with the Wiskott-Aldrich syndrome: a follow-up study". Clinical and experimental immunology 25 (2): 256-263. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
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别名
- WAS
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背景
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Synonyms: Wiskott-Aldrich syndrome protein,WASp,WAS,IMD2,
Tissue Specificity: Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen. .
Background: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, ly or inly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
Sequence Similarities: Contains 1 CRIB domain.
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分子量
- 53 kDa
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基因ID
- 7454
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UniProt
- P42768
抗原
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