Transglutaminase 2 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Transglutaminase 2 抗体 (N-Term) (ABIN3043946)
抗原
See all Transglutaminase 2 (TGM2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- Anti-Transglutaminase 2/TGM2 Antibody
-
序列
- LERCDLELET NGRDHHTADL CREKLVVR
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- different from the related mouse sequence by five amino acids.
-
产品特性
- Anti-Transglutaminase 2/TGM2 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human TGM2, different from the related mouse sequence by five amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
- Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Mouse, Rat, -Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Human, Rat
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
-
别名
- TGM2
-
背景
-
Background: Tissue transglutaminase, also called TGC, is a 78- kDa, calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. By fluorescence in situ hybridization (FISH), this gene is mapped in 20q11.23. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease.
Gene Full Name: transglutaminase 2
Sequence Similarities: Belongs to the transglutaminase superfamily. Transglutaminase family.
-
分子量
- 77 kDa
-
基因ID
- 7052
-
UniProt
- P21980
-
途径
- Tube Formation, Thromboxane A2 Receptor Signaling
抗原
-