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SFTPA2 抗体 (C-Term)

SFTPA2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043922
发货至: 中国
  • 抗原 See all SFTPA2 抗体
    SFTPA2 (Surfactant Associated Protein A2 (SFTPA2))
    抗原表位
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 206-237, C-Term
    适用
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFTPA2 antibody is un-conjugated
    应用范围
    • 14
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Anti-SFTPA1/2 Antibody Picoband®
    序列
    VNYTNWYRGE PAGRGKEQCV EMYTDGQWND RN
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SFTPA1/2 Antibody Picoband® (ABIN3043922). Tested in IF, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1/2, different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.
    亚型
    IgG
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat, -
    Immunofluorescence, 5 μg/mL, Rat
    1. Perez-Gil J, Weaver TE (June 2010). "Pulmonary surfactant pathophysiology: current models and open questions".Physiology (Bethesda) 25 (3): 132-41. 2. Phelps DS (2001). "Surfactant regulation of host defense function in the lung: a question of balance". Pediatr Pathol Mol Med 20 (4): 269-92.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    SFTPA2 (Surfactant Associated Protein A2 (SFTPA2))
    别名
    SFTPA2 (SFTPA2 产品)
    背景

    Synonyms: Pulmonary surfactant-associated protein A2,PSP-A,PSPA,SP-A,SP-A2,35 kDa pulmonary surfactant-associated protein,Alveolar proteinosis protein,Collectin-5,SFTPA2,COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B,

    Tissue Specificity: Expressed in B-cell lines and T-lymphocytes. .

    Background: SFTPA1/2 is also known as SP-A. SFTPA1 encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. SFTPA2 is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.

    Sequence Similarities: Belongs to the SFTPA family.

    分子量
    26 kDa
    基因ID
    653509, 729238
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