Peroxiredoxin 5 抗体 (AA 66-198)
Quick Overview for Peroxiredoxin 5 抗体 (AA 66-198) (ABIN3043906)
抗原
See all Peroxiredoxin 5 (PRDX5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-198
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原理
- Anti-Peroxiredoxin 5/PRDX5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Peroxiredoxin 5/PRDX5 Antibody Picoband® (ABIN3043906). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Peroxiredoxin 5 recombinant protein (Position: E66-D198). Human Peroxiredoxin 5 shares 91% amino acid (aa) sequence identity with both mouse and rat Peroxiredoxin 5.
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亚型
- IgG
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anti-Peroxiredoxin 5 (PRDX5) (AA 1-162) antibody
PRDX5 适用: 人 WB, IHC, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (AA 49-210) antibodyPRDX5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (AA 53-214) antibodyPRDX5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (AA 105-214) antibodyPRDX5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) antibodyPRDX5 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (AA 1-214) antibodyPRDX5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (C-Term) antibodyPRDX5 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (AA 1-210) antibodyPRDX5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (AA 1-213) antibodyPRDX5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 5 (PRDX5) (Middle Region) antibodyPRDX5 适用: 人, 小鼠, 大鼠, 山羊, 犬, 豚鼠, 马, 绵羊, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Budanov, A. V., Sablina, A. A., Feinstein, E., Koonin, E. V., Chumakov, P. M. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science 304: 596-600, 2004. 2. Knoops, B., Clippe, A., Bogard, C., Arsalane, K., Wattiez, R., Hermans, C., Duconseille, E., Falmagne, P., Bernard, A. Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family. J. Biol. Chem. 274: 30451-30458, 1999. 3. Wang, M.-X., Wei, A., Yuan, J., Trickett, A., Knoops, B., Murrell, G. A. C. Expression and regulation of peroxiredoxin 5 in human osteoarthritis. FEBS Lett. 531: 359-362, 2002. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Peroxiredoxin 5 (PRDX5)
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别名
- PRDX5
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背景
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Synonyms: Peroxiredoxin-5, mitochondrial,1.11.1.15,Alu corepressor 1,Antioxidant enzyme B166,AOEB166,Liver tissue 2D-page spot 71B,PLP,Peroxiredoxin V,Prx-V,Peroxisomal antioxidant enzyme,TPx type VI,Thioredoxin peroxidase PMP20,Thioredoxin reductase,PRDX5,ACR1,SBBI10,
Tissue Specificity: Widely expressed. .
Background: PRDX5 (peroxiredoxin 5) also known as AOEB166, ACR1,B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. The PRDX5 gene is mapped to11q13.1. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines. Functional analysis showed that PRDX5 has antioxidant activity equivalent to that of CAT. While PRDX5 was localized to fibroblasts in normal tendon, it was localized to fibroblasts and endothelial cells in degenerative tendon. PRDX5 mRNA and protein levels increased at 12 hours, and the increase in PRDX5 expression correlated with reduced peroxide levels. PRDX5 plays a protective role against oxidative stress in human cartilage.
Sequence Similarities: Belongs to the peroxiredoxin 2 family.
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分子量
- 22 kDa
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基因ID
- 25824
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UniProt
- P30044
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途径
- Cell RedoxHomeostasis
抗原
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