Peroxiredoxin 4 抗体 (C-Term)
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Quick Overview for Peroxiredoxin 4 抗体 (C-Term) (ABIN3043905)
抗原
See all Peroxiredoxin 4 (PRDX4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Peroxiredoxin 4/PRDX4 Antibody
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序列
- SDLTHQISKD YGVYLEDSGH TLRGLFIIDD K
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse,rat sequences by one amino acid.
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产品特性
- Anti-Peroxiredoxin 4/PRDX4 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 4, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Peroxiredoxin 4 (PRDX4) (AA 1-271) antibody
PRDX4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Peroxiredoxin 4 (PRDX4) antibodyKD Validated PRDX4 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB1570 unconjugated Recombinant Antibody
anti-Peroxiredoxin 4 (PRDX4) antibodyPRDX4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Peroxiredoxin 4 (PRDX4) (AA 14-258) antibodyPRDX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 4 (PRDX4) (AA 6-249) antibodyPRDX4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 4 (PRDX4) (AA 51-150) antibodyPRDX4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Peroxiredoxin 4 (PRDX4) (AA 82-110) antibodyPRDX4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB20891 unconjugated
anti-Peroxiredoxin 4 (PRDX4) (AA 38-271) antibodyPRDX4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 4 (PRDX4) antibodyPRDX4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 4 (PRDX4) (AA 51-150) antibodyPRDX4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C3 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Immunocytochemistry , 0.5-1 μg/mL, Human, - Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Peroxiredoxin 4 (PRDX4)
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别名
- PRDX4
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背景
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Background: PRDX4 (peroxiredoxin 4) is also known as AOE37-2. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. Functional analysis showed that PRDX4 protects glutamine synthetase from inactivation. Yeast 2-hybrid, immunoprecipitation, and immunoblot analyses indicated that PRDX4 and PRDX1 are capable of homodimerization and heterodimerization with each other but not with the mitochondrial PRDX3. Gel mobility shift and immunoblot analysis found that PRDX4 depletes NFKB binding activity together with a reduction in the amounts of p50, p65, and phosphorylated IKBA, as well as a reduction in the expression of HIV-1 viral proteins. Expression of PRDX4, alone or with PRDX1, increased the resistance of yeast cells to oxidant-induced toxicity. Jin et al. suggested PRDX4 modulates IKBA phosphorylation in the cytoplasm and thus affects a peroxiredoxin-dependent redox step.
Gene Full Name: peroxiredoxin 4
Sequence Similarities: Belongs to the AhpC/TSA family.
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分子量
- 31 kDa
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基因ID
- 10549
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UniProt
- Q13162
抗原
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