PDIA3 抗体 (C-Term)
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北京 101111
Quick Overview for PDIA3 抗体 (C-Term) (ABIN3043898)
抗原
See all PDIA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-ERp57/PDIA3 Antibody
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序列
- RELSDFISYL QREATNPPVI QEEKPKKKKK AQEDL
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse,rat sequences by two amino acids.
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产品特性
- Anti-ERp57/PDIA3 Antibody. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ERp57, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (C-Term) antibody
PDIA3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 猴, Cow, 兔, Pig, Hamster, 马, 山羊, 绵羊, Avian, Cat, 小鸡, 驴 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 1-505) antibodyPDIA3 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibodyPDIA3 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 140-505) antibodyPDIA3 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (C-Term) antibodyPDIA3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibodyPDIA3 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Map-ERp57 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 1-505) antibodyPDIA3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 446-475), (C-Term) antibodyPDIA3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20877 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 192-220) antibodyPDIA3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20876 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibody (Atto 390)PDIA3 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Map-ERp57 Atto 390
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Immunohistochemistry (Frozen Section), 0.5-1 μg/mL Immunocytochemistry/Immunofluorescence, 2 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Redox proteomics identification of specifically carbonylated proteins in the hippocampi of triple transgenic Alzheimer's disease mice at its earliest pathological stage." in: Journal of proteomics, Vol. 123, pp. 101-13, (2015) (PubMed).
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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别名
- PDIA3
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背景
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Background: PDIA3 (Protein disulfide isomerase family A, member 3), also called GRP58, Erp57 or ER60, is an isomerase enzyme. It is mapped on 15q15.3. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex, which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface. This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Gene Full Name: protein disulfide isomerase family A member 3
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分子量
- 57 kDa
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基因ID
- 2923
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UniProt
- P30101
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途径
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
抗原
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