Monoamine Oxidase B 抗体 (C-Term)
Quick Overview for Monoamine Oxidase B 抗体 (C-Term) (ABIN3043873)
抗原
See all Monoamine Oxidase B (MAOB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 448-484, C-Term
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原理
- Anti-Monoamine Oxidase B/MAOB Antibody Picoband®
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序列
- REILHAMGKI PEDEIWQSEP ESVDVPAQPI TTTFLER
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Monoamine Oxidase B/MAOB Antibody Picoband® (ABIN3043873). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MAOB, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
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亚型
- IgG
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anti-Monoamine Oxidase B (MAOB) antibody
MAOB 适用: 人 WB, ELISA, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (AA 206-505) antibodyMAOB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (Internal Region) antibodyVerified MAOB 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (AA 1-260) antibodyMAOB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (AA 1-520) antibodyMAOB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (AA 1-520) antibodyMAOB 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (AA 51-150) antibodyMAOB 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) (AA 2-489) antibodyMAOB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Monoamine Oxidase B (MAOB) antibodyMAOB 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 9B6 unconjugated Recombinant Antibody
anti-Monoamine Oxidase B (MAOB) (Internal Region) antibodyMAOB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
1. Bach, A. W., Lan, N. C., Johnson, D. L., Abell, C. W., Bembenek, M. E., Kwan, S.-W., Seeburg, P. H., Shih, J. C. cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc. Nat. Acad. Sci. 85: 4934-4938, 1988. 2. Binda, C., Newton-Vinson, P., Hubalek, F., Edmondson, D. E., Mattevi, A. Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders. Nature Struct. Biol. 9: 22-26, 2002. 3. Edmondson DE, Binda C, Mattevi A (2007). "STRUCTURAL INSIGHTS INTO THE MECHANISM OF AMINE OXIDATION BY MONOAMINE OXIDASES A AND B". Archives of Biochemistry and Biophysics 464 (2): 269-76. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Monoamine Oxidase B (MAOB)
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别名
- MAOB
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背景
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Synonyms: Amine oxidase [flavin-containing] B,1.4.3.4,Monoamine oxidase type B,MAO-B,MAOB,
Tissue Specificity: Heart, liver, duodenum, blood vessels and kidney.
Background: MAOB (MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.
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分子量
- 59 kDa
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基因ID
- 4129
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UniProt
- P27338
抗原
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