KCNMA1 抗体 (AA 124-467)
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北京 101111
Quick Overview for KCNMA1 抗体 (AA 124-467) (ABIN3043867)
抗原
See all KCNMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-467
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原理
- Anti-Maxi Potassium channel alpha/KCNMA1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Maxi Potassium channel alpha/KCNMA1 Antibody (ABIN3043867). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KCNMA1 recombinant protein (Position: K124-Q467). Human KCNMA1 shares 99% amino acid (aa) sequence identity with both mouse and rat KCNMA1.
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亚型
- IgG
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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (C-Term) antibody
KCNMA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 兔, 犬, 马, 豚鼠, 绵羊 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1-86) antibodyKCNMA1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 199-213), (Extracellular) antibodyKCNMA1 适用: 大鼠 IHC, WB, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1131-1236) antibodyKCNMA1 适用: 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1080-1129) antibodyKCNMA1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 绵羊, 小鸡, 非洲爪蟾, 猴, Pig, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (Internal Region) antibodyKCNMA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 兔, 犬, 小鸡, 非洲爪蟾, 猴, Pig, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1184-1200), (Intracellular) antibodyKO Validated KCNMA1 适用: 小鼠 IHC, WB, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1097-1196), (Intracellular) antibodyKCNMA1 适用: 小鼠 WB 宿主: 豚鼠 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (Internal Region) antibodyKCNMA1 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 118-152) antibodyKCNMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53642 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
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别名
- KCNMA1
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背景
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Synonyms: Calcium-activated potassium channel subunit alpha-1,BK channel,BKCA alpha,Calcium-activated potassium channel, subfamily M subunit alpha-1,K (VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,Slo homolog,hSlo,KCNMA1,KCNMA, SLO,
Tissue Specificity: Widely expressed. Except in myocytes, it is almost ubiquitously expressed. .
Background: Calcium-activated potassium channel subunit alpha-1 also known as KCa1.1, or BK channel for short, is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes. This gene is located on 10q22.3. BK channels are activated (opened) by changes in membrane electrical potential and/or by increases in concentration of intracellular calcium ion (Ca2+). It is essential for the regulation of several key physiological processes including smooth muscle tone and neuronal excitability. BK channels also contribute to the behavioral effects of ethanol in the worm C. elegans under high concentrations (> 100 mM, or approximately 0.50 % BAC).It remains to be determined if BK channels contribute to intoxication in humans.
Sequence Similarities: Belongs to the potassium channel family. Calcium- activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
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分子量
- 110-138 kDa
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基因ID
- 3778
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UniProt
- Q12791
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途径
- Regulation of Hormone Metabolic Process, Sensory Perception of Sound
抗原
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