HDAC11 抗体 (N-Term)
Quick Overview for HDAC11 抗体 (N-Term) (ABIN3043840)
抗原
See all HDAC11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 47-81, N-Term
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原理
- Anti-HDAC11 Antibody Picoband®
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序列
- NFLKEEKLLS DSMLVEAREA SEEDLLVVHT RRYLN
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-HDAC11 Antibody Picoband® (ABIN3043840). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Histone Deacetylase 11 (HDAC11) (AA 1-347) antibody
HDAC11 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C2-2G5 unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 1-30), (N-Term) antibodyHDAC11 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2588 unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 1-347) antibodyHDAC11 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 11 (HDAC11) antibodyHDAC11 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 11 (HDAC11) antibodyHDAC11 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 313-345), (C-Term) antibodyHDAC11 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2589 unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 21-120) antibodyHDAC11 适用: 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 1-347) antibodyHDAC11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 1-347) antibodyHDAC11 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 11 (HDAC11) (AA 146-195) antibodyHDAC11 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Bat, 小鸡, Pig, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: HDAC11 histone deacetylase 11". 2. Gao L, Cueto MA, Asselbergs F, Atadja P (Jul 2002). "Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family".The Journal of Biological Chemistry 277(28): 25748-55. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HDAC11 (Histone Deacetylase 11 (HDAC11))
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别名
- HDAC11
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背景
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Synonyms: Histone deacetylase 11,HD11,3.5.1.98,HDAC11,
Tissue Specificity: Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
Background: Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.
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分子量
- 37 kDa
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基因ID
- 79885
抗原
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