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GRIA2 抗体 (AA 25-360)

Name: GRIA2 抗体 (AA 25-360)
SKU: ABIN3043838
Availability: OutOfStock

GRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Anti- GRIA2 antibody, Western blotting All lanes: Anti GRIA2 at 0. (GRIA2 抗体 (AA 25-360))

Anti- GRIA2 antibody, IHC(P) IHC(P): Rat Brain Tissue (GRIA2 抗体 (AA 25-360))

IHC

Anti- GRIA2 antibody, IHC(P) IHC(P): Mouse Brain Tissue (GRIA2 抗体 (AA 25-360))

IHC

3 images

(2 references)

产品编号 ABIN3043838

发货至: 中国

Datasheet as PDF

抗原 See all GRIA2 抗体

GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
抗原表位
25

16

6

6

6

6

3

3

2

2

2

2

2

1

1

1

1

1

1

1
AA 25-360
适用
92

71

56

9

8

7

5

4

4

4

3

2

2

1

1
人, 大鼠, 小鼠
宿主
86

26

1
兔
Compatible Secondaries
克隆类型
75

38
多克隆
标记
64

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This GRIA2 antibody is un-conjugated
应用范围
90

44

25

25

25

24

24

16

13

12

6

3

3

2

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Anti-Ionotropic Glutamate receptor 2/GRIA2 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Ionotropic Glutamate receptor 2/GRIA2 Antibody Picoband® (ABIN3043838). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human GRIA2 recombinant protein (Position: N25-I360). Human GRIA2 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA2.

亚型

IgG

Top Product

Discover our top product GRIA2 Primary Antibody
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody
GRIA2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7G6 unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 35-175) antibody
GRIA2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A7A3 unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibody
GRIA2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 413-527) antibody
GRIA2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 175-430) antibody
GRIA2 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibody
GRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibody
GRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibody
GRIA2 适用: 大鼠 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S21-32 unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 151-250) antibody
GRIA2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Ser432) antibody
GRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat
Immunocytochemistry, 0.5-1 μg/mL, Human
Immunofluorescence, 2 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. Armstrong, N., Gouaux, E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28: 165-181, 2000. 2. Biou, V., Bhattacharyya, S., Malenka, R. C. Endocytosis and recycling of AMPA receptors lacking GluR2/3. Proc. Nat. Acad. Sci. 105: 1038-1043, 2008. 3. Mameli, M., Balland, B., Lujan, R., Luscher, C. Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental area. Science 317: 530-533, 2007.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Liu, Mei, Li, Roboti, Pang, Ying, Gao, Lowe, Bao: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).

Dai, Li, Zhong, Chen, Cheng, Liu, Li: "The paracrine effect of cobalt chloride on BMSCs during cognitive function rescue in the HIBD rat." in: Behavioural brain research, Vol. 332, pp. 99-109, (2017) (PubMed).
抗原

GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

别名

GRIA2 (GRIA2 产品)

背景

Synonyms: Glutamate receptor 2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic, AMPA 2,GluA2,GRIA2,GLUR2,
Tissue Specificity: Widely expressed in brain.
Background: Glutamate receptor 2, also known as GLUR2, is a protein that in humans is encoded by the GRIA2 gene. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. GLUR2's cytogenetic location is 4q32.1. The crystal structures of the GLUR2 ligand-binding core in the apo state and in the presence of the antagonist DNQX, the partial agonist kainate, and the full agonists AMPA and glutamate.GLUR2 plays a major role in depression at synapses in which glutamate remains in the synaptic cleft for prolonged periods of time during normal operation of the synapse. The overexpression of GLUR2 increases dendritic spine size and density in hippocampal neurons, and more remarkably, induces spine formation in GABA-releasing interneurons that normally lack spines.

分子量

110 kDa

基因ID

14800

UniProt

P42262

途径

PI3K-Akt Signaling