Glutathione Peroxidase 1 抗体 (Middle Region)
Quick Overview for Glutathione Peroxidase 1 抗体 (Middle Region) (ABIN3043834)
抗原
See all Glutathione Peroxidase 1 (GPX1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 116-146, Middle Region
-
原理
- Anti-Glutathione Peroxidase 1/GPX1 Antibody Picoband®
-
序列
- EVNGAGAHPL FAFLREALPA PSDDATALMT D
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Glutathione Peroxidase 1/GPX1 Antibody Picoband® (ABIN3043834). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human GPX1, different from the related mouse sequence by six amino acids and from the related rat sequence by five amino acids.
-
亚型
- IgG
-
-
anti-Glutathione Peroxidase 1 (GPX1) (AA 50-203) antibody
GPX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 164-193), (C-Term) antibodyGPX1 适用: 人, 小鼠, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22987 unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (Internal Region) antibodyVerified GPX1 适用: 人, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 50-203) antibodyGPX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 48-201) antibodyGPX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 127-193) antibodyGPX1 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 169-199), (C-Term) antibodyGPX1 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 51-150) antibodyGPX1 适用: 人, 小鼠, Pig, 绵羊 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 48-201) antibodyGPX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) antibodyGPX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
1. Kiss C, Li J, Szeles A, Gizatullin RZ, Kashuba VI, Lushnikova T, Protopopov AI, Kelve M, Kiss H, Kholodnyuk ID, Imreh S, Klein G, Zabarovsky ER (Jun 1998). "Assignment of the ARHA and GPX1 genes to human chromosome bands 3p21.3 by in situ hybridization and with somatic cell hybrids". Cytogenet Cell Genet 79 (3-4): 228-30. 2. "Entrez Gene: GPX1 glutathione peroxidase 1" -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Glutathione Peroxidase 1 (GPX1)
-
别名
- GPX1
-
背景
-
Synonyms: Glutathione peroxidase 1,GPx-1,GSHPx-1,1.11.1.9,Cellular glutathione peroxidase,GPX1,
Tissue Specificity: T-cells and endothelial cells.
Background: Glutathione peroxidase 1, also known as, GPX-1 is an enzyme that in humans is encoded by the GPX1 gene. It is mapped to 3p21.31. This gene encodes a member of the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. GPX1 is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.
Sequence Similarities: Belongs to the glutathione peroxidase family.
-
分子量
- 22 kDa
-
基因ID
- 2876
-
UniProt
- P07203
-
途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
-
