CNTF 抗体 (AA 2-200)
Quick Overview for CNTF 抗体 (AA 2-200) (ABIN3043814)
抗原
See all CNTF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-200
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原理
- Anti-CNTF Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CNTF Antibody Picoband® (ABIN3043814). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84% and 95% amino acid (aa) sequences identity with human and mouse CNTF, respectively.
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亚型
- IgG
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anti-Ciliary Neurotrophic Factor (CNTF) (C-Term) antibody
CNTF 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 1-200) antibodyCNTF 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-198) antibodyCNTF 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 21-150) antibodyCNTF 适用: 人, 大鼠, 兔 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-198) antibodyCNTF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 2-200) antibodyCNTF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 4-196) antibodyCNTF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) (AA 1-200) antibodyCNTF 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ciliary Neurotrophic Factor (CNTF) antibody (Biotin)CNTF 适用: 大鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
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ELISA, 0.1-0.5 μg/mL, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Rat
1. Barbin, G., Manthorpe, M., Varon, S. Purification of the chick eye ciliary neuronotrophic factor. J. Neurochem. 43: 1468-1478, 1984. 2. Raju, S. V. Y., Zheng, M., Schuleri, K. H., Phan, A. C., Bedja, D., Saraiva, R. M., Yiginer, O., Vandegaer, K., Gabrielson, K. L., O'Donnell, C. P., Berkowitz, D. E., Barouch, L. A., Hare, J. M. Activation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesity. Proc. Nat. Acad. Sci. 103: 4222-4227, 2006. 3. Sendtner, M., Schmalbruch, H., Stockli, K. A., Carroll, P., Kreutzberg, G. W., Thoenen, H.Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358: 502-504, 1992. 4. Emerich, D. F., Winn, S. R., Hantraye, P. M., Peschanski, M., Chen, E.-Y., Chu, Y., McDermott, P., Baetge, E. E., Kordower, J. H. Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease.Nature 386: 395-399, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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别名
- CNTF
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背景
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Synonyms: Ciliary neurotrophic factor,CNTF,Cntf,
Tissue Specificity: Nervous system.
Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. CNTF appears not to be involved in motor neuron survival during development. human CNTF has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.
Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.
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分子量
- 23 kDa
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基因ID
- 25707
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UniProt
- P20294
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途径
- JAK/STAT Signaling
抗原
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