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CLOCK 抗体 (N-Term)

CLOCK 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Clock Homolog (Mouse) (CLOCK) (AA 75-109), (N-Term) antibody (ABIN3043813) (CLOCK 抗体 (N-Term))

Anti- KAT13D/CLOCK antibody, IHC(P) IHC(P): Mouse Skeletal Muscle Tissue (CLOCK 抗体 (N-Term))

IHC analysis of CLOCK using anti-CLOCK antibody . (CLOCK 抗体 (N-Term))

Anti- KAT13D/CLOCK antibody, IHC(P) IHC(P): Rat Testis Tissue (CLOCK 抗体 (N-Term))

IHC analysis of CLOCK using anti-CLOCK antibody . (CLOCK 抗体 (N-Term))

IHC analysis of CLOCK using anti-CLOCK antibody . (CLOCK 抗体 (N-Term))

IHC analysis of CLOCK using anti-CLOCK antibody . (CLOCK 抗体 (N-Term))

Anti- KAT13D/CLOCK antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue (CLOCK 抗体 (N-Term))

8 images

产品编号 ABIN3043813

发货至: 中国

Datasheet as PDF

抗原 See all CLOCK 抗体

CLOCK (Clock Homolog (Mouse) (CLOCK))
抗原表位
6

3

3

2

2

2

2

1

1

1

1

1

1

1

1
AA 75-109, N-Term
适用
45

27

21

2

2

2

2

2

2

1

1

1
人, 小鼠, 大鼠, 猴
宿主
38

6

1

1
兔
Compatible Secondaries
克隆类型
33

13
多克隆
标记
28

3

2

2

2

2

2

2

2

1
This CLOCK antibody is un-conjugated
应用范围
23

17

10

5

5

5

4

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

原理

Anti-KAT13D/CLOCK Antibody Picoband®

序列

QKSIDFLRKH KEITAQSDAS EIRQDWKPTF LSNEE

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-KAT13D/CLOCK Picoband® Antibody (ABIN3043813). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human KAT13D/CLOCK, different from the related mouse sequence by one amino acid, and identical to the related rat sequence.

亚型

IgG
anti-Clock Homolog (Mouse) (CLOCK) (Internal Region) antibody
CLOCK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (AA 577-846) antibody
CLOCK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (AA 577-846) antibody
CLOCK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) antibody
CLOCK 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8F7 unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (AA 497-596) antibody
CLOCK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (C-Term) antibody
CLOCK 适用: 人, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) antibody
CLOCK 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8F7 unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (AA 34-379) antibody
CLOCK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (Internal Region) antibody
CLOCK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Clock Homolog (Mouse) (CLOCK) (AA 458-472) antibody
Verified CLOCK 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Monkey, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
1. Dunlap JC (Jan 1999). "Molecular bases for circadian clocks". Cell 96 (2): 271-90. 2. King DP, Zhao Y, Sangoram AM, Wilsbacher LD, Tanaka M, Antoch MP, Steeves TD, Vitaterna MH, Kornhauser JM, Lowrey PL, Turek FW, Takahashi JS (May 1997). "Positional cloning of the mouse circadian clock gene". Cell 89 (4): 641-653. 3. Vitaterna MH, King DP, Chang AM, Kornhauser JM, Lowrey PL, McDonald JD, Dove WF, Pinto LH, Turek FW, Takahashi JS (Apr 1994). "Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior". Science 264 (5159): 719-25.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CLOCK (Clock Homolog (Mouse) (CLOCK))

别名

CLOCK (CLOCK 产品)

背景

Clock (Circadian Locomotor Output Cycles Kaput) is also known as KAT13D. The protein encoded by this gene plays a central role in the regulation of circadian rhythms. This protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. And the encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.

分子量

110 kDa

基因ID

9575

UniProt

O15516

途径

Regulation of Lipid Metabolism by PPARalpha, Photoperiodism

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