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Caveolin-1 抗体 (AA 4-178)

Name: Caveolin-1 抗体 (AA 4-178)
SKU: ABIN3043803
Availability: OutOfStock

CAV1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibody (ABIN3043803) (Caveolin-1 抗体 (AA 4-178))

Anti- Caveolin-1 picoband antibody, IHC(P): Human Lung Cancer Tissue (Caveolin-1 抗体 (AA 4-178))

IHC

Anti- Caveolin-1 picoband antibody, IHC(P) IHC(P): Human Placenta Tissue (Caveolin-1 抗体 (AA 4-178))

IHC

Anti- Caveolin-1 picoband antibody, ICC ICC: A549 Cell (Caveolin-1 抗体 (AA 4-178))

IHC

Anti- Caveolin-1 picoband antibody, Western blotting All lanes: Anti Caveolin-1 at 0. (Caveolin-1 抗体 (AA 4-178))

5 images

(2 references)

产品编号 ABIN3043803

发货至: 中国

Datasheet as PDF

抗原 See all Caveolin-1 (CAV1) 抗体

Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
抗原表位
15

15

8

6

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 4-178
适用
100

56

40

11

9

8

8

8

7

7

5

3

2

1

1

1

1

1

1

1

1

1

1
人, 大鼠, 小鼠
宿主
89

10

5

2
兔
Compatible Secondaries
克隆类型
83

23
多克隆
标记
72

6

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Caveolin-1 antibody is un-conjugated
应用范围
83

30

25

22

17

17

15

15

9

8

4

2

2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

原理

Anti-Caveolin-1/CAV1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Caveolin-1/CAV1 Antibody Picoband® (ABIN3043803). Tested in Flow Cytometry, IF, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Caveolin-1 recombinant protein (Position: G4-I178). Human Caveolin-1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Caveolin-1, respectively.

亚型

IgG

Top Product

Discover our top product CAV1 Primary Antibody
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
KO Validated CAV1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-105) antibody
CAV1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-100) antibody
CAV1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-120) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibody
CAV1 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (pTyr14) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (C-Term) antibody
CAV1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Immunohistochemistry (Frozen Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human1. Tahir, S. A., Yang, G., Ebara, S., Timme, T. L., Satoh, T., Li, L., Goltsov, A., Ittmann, M., Morrisett, J. D., Thompson, T. C.Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer.Cancer Res. 61: 3882-3885, 2001. 2. Wang, X. M., Zhang, Y., Kim, H. P., Zhou, Z., Feghali-Bostwick, C. A., Liu, F., Ifedigbo, E., Xu, X., Oury, T. D., Kaminski, N., Choi, A. M. K.Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.J. Exp. Med. 203: 2895-2906, 2006. 3. Yang, G., Truong, L. D., Timme, T. L., Ren, C., Wheeler, T. M., Park, S. H., Nasu, Y., Bangma, C. H., Kattan, M. W., Scardino, P. T., Thompson, T. C.Elevated expression of caveolin is associated with prostate and breast cancer.Clin. Cancer Res. 4: 1873-1880, 1998.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Shi, Li, Jia, Ji, Song, Cheng, Wu, Song, Zhang, Zhu, Yang: "MicroRNA-199a-5p affects porcine preadipocyte proliferation and differentiation." in: International journal of molecular sciences, Vol. 15, Issue 5, pp. 8526-38, (2015) (PubMed).

Wang, Zhao, Wu, He, Qu, Zhao, Zhao, Li, Wang: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
抗原

Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

别名

CAV1 (CAV1 产品)

背景

Synonyms: Caveolin-1,CAV1,CAV,
Tissue Specificity: Expressed in muscle and lung, less so in liver, brain and kidney.
Background: CAV1 ( Caveolin-1) is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
Sequence Similarities: Belongs to the caveolin family.

分子量

22 kDa

基因ID

857

UniProt

Q03135

途径

Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals