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ATP5H 抗体 (AA 2-161)

This anti-ATP5H antibody is a 兔 多克隆 antibody detecting ATP5H in WB, IHC, IF 和 ICC. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN3043795
发货至: 中国

Quick Overview for ATP5H 抗体 (AA 2-161) (ABIN3043795)

抗原

See all ATP5H 抗体
ATP5H (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit D (ATP5H))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This ATP5H antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 2-161

    原理

    Anti-ATP5H Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ATP5H Antibody Picoband® (ABIN3043795). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATP5H recombinant protein (Position: A2-L161). Human ATP5H shares 81% and 78% amino acid (aa) sequence identity with mouse and rat ATP5H, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section),2-5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    1. Boada M, et al. ATP5H/KCTD2 locus is associated with Alzheimer's disease risk. Mol Psychiatry, 2014 Jun. 2. Kim DW, et al. Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells. Cancer Sci, 2008 Oct.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ATP5H (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit D (ATP5H))

    别名

    ATP5H

    背景

    Synonyms: ATP synthase subunit d, mitochondrial,ATPase subunit d,ATP5H,My032,

    Tissue Specificity: Occurs in all lipoprotein fractions in plasma. It constitutes 10-20 % of very low density lipoproteins (VLDL) and 1-2 % of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.

    Background: ATP5H is also known as ATPQ. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.

    Sequence Similarities: Belongs to the apolipoprotein A1/A4/E family.

    分子量

    22 kDa

    基因ID

    10476

    UniProt

    O75947

    途径

    Proton Transport, Ribonucleoside Biosynthetic Process
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