ATP2A3 抗体 (N-Term)
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北京 101111
Quick Overview for ATP2A3 抗体 (N-Term) (ABIN3043794)
抗原
See all ATP2A3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-SERCA3 ATPase/ATP2A3 Antibody
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序列
- MEAAHLLPAA DVLRHFSVTA EGGLSPAQVT
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by five amino acids,and from the related rat sequence by six amino acids.
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产品特性
- Anti-SERCA3 ATPase/ATP2A3 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human ATP2A3, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
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亚型
- IgG
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anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (AA 501-620) antibody
ATP2A3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2H3 unconjugated
anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (AA 501-621) antibodyATP2A3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H3 unconjugated
anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (N-Term) antibodyATP2A3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (AA 13-47) antibodyATP2A3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53548 unconjugated
anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (AA 101-200) antibodyATP2A3 适用: 人, 非洲爪蟾, Xenopus tropicalis WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (AA 828-877) antibodyATP2A3 适用: 人, Cow, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Ubiquitous (ATP2A3) (AA 981-993), (C-Term), (Cytosolic) antibodyATP2A3 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, HumanWestern blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
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别名
- ATP2A3
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背景
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Background: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, also known as SERCA3, is anenzyme that in humans is encoded by the ATP2A3 gene. It is mapped to 17p13.2. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of cells. ATP2A3 expression was originally described as non-muscular, but was recently observed in cardiomyocyte. What's more, the expression of ATP2A3 was significantly reduced or lost in colon carcinomas compared with normal colonic epithelial cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.
Gene Full Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Sequence Similarities: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
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分子量
- 114 kDa
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基因ID
- 489
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UniProt
- Q93084
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途径
- Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process
抗原
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