APLP1 抗体 (N-Term)
Quick Overview for APLP1 抗体 (N-Term) (ABIN3043786)
抗原
See all APLP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 82-112, N-Term
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原理
- Anti-APLP1 Antibody Picoband®
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序列
- RRCLRDPQRV LEYCRQMYPE LQIARVEQAT Q
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-APLP1 Antibody Picoband® (ABIN3043786). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human APLP1, different from the related mouse sequence by three amino acids.
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亚型
- IgG
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anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 39-300) antibody
APLP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) antibodyAPLP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 505-539) antibodyAPLP1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB58020 unconjugated
anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 1-100) antibodyAPLP1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 39-300) antibodyAPLP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) antibodyAPLP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor-Like Protein 1 (APLP1) (AA 1-650) antibodyAPLP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1.Lenkkeri, U., Kestila, M., Lamerdin, J., McCready, P., Adamson, A., Olsen, A., Tryggvason, K. Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1. Hum. Genet. 102: 192-196, 1998. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
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别名
- APLP1
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背景
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Synonyms: Amyloid-like protein 1,APLP,APLP-1,C30,APLP1,
Tissue Specificity: Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). .
Background: Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
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分子量
- 85 kDa
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基因ID
- 333
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UniProt
- P51693
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途径
- cAMP Metabolic Process
抗原
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