Caveolin 2 抗体 (AA 1-162)
(1 reference)Quick Overview for Caveolin 2 抗体 (AA 1-162) (ABIN3043749)
抗原
See all Caveolin 2 (CAV2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-162
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原理
- Anti-Caveolin-2/CAV2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Caveolin-2/CAV2 Antibody Picoband® (ABIN3043749). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Caveolin-2 recombinant protein (Position: M1-D162). Human Caveolin-2 shares 90% and 89% amino acid (aa) sequences identity with mouse and rat Caveolin-2, respectively.
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亚型
- IgG
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anti-Caveolin 2 (CAV2) (N-Term) antibody
CAV2 适用: 人 WB, IHC (p), IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 1-86) antibodyCAV2 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5E9E2 unconjugated
anti-Caveolin 2 (CAV2) (N-Term) antibodyCAV2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 猴, 马, Pig, Hamster, 山羊, 驴, 小鸡, Cat, Avian WB, IHC (p), IF, IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 1-17) antibodyCAV2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 3-64) antibodyCAV2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) antibodyCAV2 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 1-17), (N-Term) antibodyCAV2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) (AA 11-44), (N-Term) antibodyCAV2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB16483 unconjugated
anti-Caveolin 2 (CAV2) (N-Term) antibodyCAV2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 2 (CAV2) antibodyCAV2 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunofluorescence, 2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Scherer, P. E., Okamoto, T., Chun, M., Nishimoto, I., Lodish, H. F., Lisanti, M. P.Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.Proc. Nat. Acad. Sci. 93: 131-135, 1996. 2. Yamazaki, K., Mizui, Y., Tanaka, I.Radiation hybrid mapping of human ADAM10 gene to chromosome 15.Genomics 45: 457-459, 1997. 2. Galbiati, F., Volonte, D., Gil, O., Zanazzi, G., Salzer, J. L., Sargiacomo, M., Scherer, P. E., Engelman, J. A., Schlegel, A., Parenti, M., Okamoto, T., Lisanti, M. P.Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury.Proc. Nat. Acad. Sci. 95: 10257-10262, 1998. 3. Engelman, J. A., Zhang, X. L., Galbiati, F., Lisanti, M. P.Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3): Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31).FEBS Lett. 429: 330-336, 1998. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
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: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
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- Caveolin 2 (CAV2)
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别名
- CAV2
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背景
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Synonyms: Caveolin-2,CAV2,
Tissue Specificity: Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .
Background: Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. It is mapped to 7q31.1-q31.2. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both of them are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury.
Sequence Similarities: Belongs to the caveolin family.
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分子量
- 21 kDa
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基因ID
- 858
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UniProt
- P51636
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
抗原
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