ALOX15 抗体 (AA 2-337)
Quick Overview for ALOX15 抗体 (AA 2-337) (ABIN3043726)
抗原
See all ALOX15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-337
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原理
- Anti-15 Lipoxygenase 1/ALOX15 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-15 Lipoxygenase 1/ALOX15 Antibody Picoband® (ABIN3043726). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ALOX15 recombinant protein (Position: G2-P337). Human ALOX15 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat ALOX15, respectively.
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亚型
- IgG
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anti-Arachidonate 15-Lipoxygenase (ALOX15) antibody
ALOX15 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibodyALOX15 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 170-312) antibodyALOX15 适用: 人 WB 宿主: 小鼠 Monoclonal 6# unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (Internal Region) antibodyVerified ALOX15 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibodyALOX15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 610-643), (C-Term) antibodyALOX15 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17156 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-225) antibodyALOX15 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-663) antibodyALOX15 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) antibodyALOX15 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 170-312) antibodyALOX15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
1. Funk CD, Funk LB, FitzGerald GA, Samuelsson B (May 1992)."Characterization of human 12-lipoxygenase genes".Proceedings of the National Academy of Sciences of the United States of America 89 (9): 3962-6. 2. Kelavkar, U. P., Badr, K. F. Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator gene. Proc. Nat. Acad. Sci. 96: 4378-4383, 1999. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
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别名
- ALOX15
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背景
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Synonyms: Arachidonate 15-lipoxygenase,15-LOX,15-LOX-1,1.13.11.33,12/15-lipoxygenase,Arachidonate 12-lipoxygenase, leukocyte-type,12-LOX,1.13.11.31,Arachidonate omega-6 lipoxygenase,ALOX15,LOG15,
Tissue Specificity: Detected in monocytes and eosinophils (at protein level). Expressed in airway epithelial cells. .
Background: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in ionally opposite manners.
Sequence Similarities: Belongs to the lipoxygenase family.
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分子量
- 75 kDa
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基因ID
- 246
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UniProt
- P16050
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途径
- Regulation of Actin Filament Polymerization
抗原
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