Arylsulfatase A 抗体 (C-Term)
-
- 抗原 See all Arylsulfatase A (ARSA) 抗体
- Arylsulfatase A (ARSA)
-
抗原表位
- AA 454-482, C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Arylsulfatase A antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)
- 原理
- Anti-ARSA Antibody Picoband®
- 序列
- QALKQLQLLK AQLDAAVTFG PSQVARGED
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-ARSA Antibody Picoband® (ABIN3043722). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ARSA, different from the related mouse sequence by six amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ARSA Primary Antibody
-
anti-Arylsulfatase A (ARSA) (Internal Region) antibody
Verified ARSA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (Internal Region) antibodyARSA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 1-507) antibodyARSA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 1-507) antibodyARSA 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (AA 368-412) antibodyARSA 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) antibodyARSA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Arylsulfatase A (ARSA) (N-Term) antibodyARSA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Fujii T, Kobayashi T, Honke K et al. (1992). "Proteolytic processing of human lysosomal arylsulfatase A". Biochim. Biophys. Acta 1122 (1): 93-8. 2. Kondo R, Wakamatsu N, Yoshino H et al. (1991)."Identification of a mutation in the arylsulfatase A gene of a patient with adult-type metachromatic leukodystrophy". Am. J. Hum. Genet. 48 (5): 971-8. 3. Matzner U, Herbst E, Hedayati KK, Lüllmann-Rauch R, Wessig C, Schröder S, Eistrup C, Möller C, Fogh J, Gieselmann V (May 2005). "Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy". Hum. Mol. Genet. 14 (9): 1139-52. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
- 抗原
- Arylsulfatase A (ARSA)
- 别名
- ARSA (ARSA 产品)
- 背景
-
Synonyms: Arylsulfatase A,ASA,3.1.6.8,Cerebroside-sulfatase,Arylsulfatase A component B,Arylsulfatase A component C,ARSA,
Tissue Specificity: Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). .
Background: Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
Sequence Similarities: Belongs to the sulfatase family.
- 分子量
- 54 kDa
- 基因ID
- 410
- UniProt
- P15289
-
